{"id":3877,"date":"2023-06-09T12:00:17","date_gmt":"2023-06-09T11:00:17","guid":{"rendered":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/?p=3877"},"modified":"2024-12-02T12:41:56","modified_gmt":"2024-12-02T12:41:56","slug":"viral-emissions-into-the-air-and-environment-after-sars-cov-2-human-challenge-a-phase-1-open-label-first-in-human-study","status":"publish","type":"post","link":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/2023\/06\/09\/viral-emissions-into-the-air-and-environment-after-sars-cov-2-human-challenge-a-phase-1-open-label-first-in-human-study\/","title":{"rendered":"Viral Emissions into the Air and Environment after SARS-CoV-2 Human Challenge: A Phase 1, Open Label, First-in-Human Study"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; fullwidth=&#8221;on&#8221; next_background_color=&#8221;#000000&#8243; global_module=&#8221;322&#8243;][et_pb_fullwidth_menu global_parent=&#8221;322&#8243; _builder_version=&#8221;3.0.106&#8243; menu_id=&#8221;7&#8243; submenu_direction=&#8221;downwards&#8221; fullwidth_menu=&#8221;off&#8221; background_layout=&#8221;dark&#8221; module_class=&#8221;main-navigation&#8221; \/][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; _builder_version=&#8221;3.0.47&#8243; prev_background_color=&#8221;#000000&#8243; next_background_color=&#8221;#1d1d1d&#8221;][et_pb_column type=&#8221;2_3&#8243; specialty_columns=&#8221;2&#8243;][et_pb_row_inner _builder_version=&#8221;3.0.47&#8243; locked=&#8221;off&#8221;][et_pb_column_inner type=&#8221;4_4&#8243; saved_specialty_column_type=&#8221;2_3&#8243;][et_pb_post_title featured_placement=&#8221;above&#8221; _builder_version=&#8221;3.0.106&#8243; locked=&#8221;on&#8221;]<\/p>\n<p>[\/et_pb_post_title][et_pb_text _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p>Effectively implementing strategies to curb transmission of SARS-CoV-2 (the virus that causes COVID-19) requires understanding who is contagious and when.<\/p>\n<p>Whilst viral load (VL) on upper respiratory swabs has commonly been used to infer contagiousness, measuring viral emissions may be more accurate to indicate the chance of onward transmission and identify likely routes.<\/p>\n<p>This paper, from <a href=\"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/research-themes\/experimental-infections-of-human-and-animals-to-characterise-sars-cov2-transmission\/\"><span style=\"text-decoration: underline\">theme 5 researchers on the PROTECT NCS<\/span>,\u00a0<\/a>discusses the findings from the first human challenge study with SARS-CoV-2.<\/p>\n<p>[\/et_pb_text][et_pb_button admin_label=&#8221;Button: Read the paper&#8221; button_url=&#8221;https:\/\/doi.org\/10.1016\/S2666-5247(23)00101-5&#8243; button_text=&#8221;Read the paper&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p>[\/et_pb_button][et_pb_post_nav in_same_term=&#8221;off&#8221; prev_text=&#8221;Previous&#8221; next_text=&#8221;Next&#8221; _builder_version=&#8221;3.0.106&#8243; locked=&#8221;on&#8221;]<\/p>\n<p>[\/et_pb_post_nav][et_pb_comments _builder_version=&#8221;3.16&#8243; header_font_size_tablet=&#8221;51&#8243; header_line_height_tablet=&#8221;2&#8243; custom_button=&#8221;on&#8221; button_text_color=&#8221;#ffffff&#8221; button_use_icon=&#8221;off&#8221; locked=&#8221;on&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_text_size__hover=&#8221;null&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover=&#8221;null&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover=&#8221;null&#8221; button_text_color__hover_enabled=&#8221;off&#8221; button_text_color__hover=&#8221;null&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_one_text_color__hover=&#8221;null&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover=&#8221;null&#8221; button_border_width__hover_enabled=&#8221;off&#8221; button_border_width__hover=&#8221;null&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_one_border_width__hover=&#8221;null&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover=&#8221;null&#8221; button_border_color__hover_enabled=&#8221;off&#8221; button_border_color__hover=&#8221;null&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; button_one_border_color__hover=&#8221;null&#8221; button_two_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover=&#8221;null&#8221; button_border_radius__hover_enabled=&#8221;off&#8221; button_border_radius__hover=&#8221;null&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover=&#8221;null&#8221; 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Safety Executive \u2013 Science Division<br \/>Harpur Hill<br \/>Buxton<br \/>SK17 9JN<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243;][et_pb_text admin_label=&#8221;Connect Title&#8221; global_parent=&#8221;1519&#8243; _builder_version=&#8221;3.17.6&#8243; text_text_color=&#8221;#ffffff&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_layout=&#8221;dark&#8221;]<\/p>\n<p style=\"color: #fff !important;font-size: 1.3em;font-weight: 600\">Connect with us<\/p>\n<p>[\/et_pb_text][et_pb_code admin_label=&#8221;Social Media&#8221; global_parent=&#8221;1519&#8243; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<ul class=\"inlineList footer-socialIcons\"><!-- [et_pb_line_break_holder] --><\/p>\n<li><!-- [et_pb_line_break_holder] --> <a href=\"https:\/\/twitter.com\/PROTECT_NCS\"><!-- [et_pb_line_break_holder] --> <img loading=\"lazy\" decoding=\"async\" class=\"lazy\" src=\"\/\/assets.manchester.ac.uk\/phase1\/templates\/images\/icon-twitter-50.png\" alt=\"Twitter page for the PROTECT National Core Study.\" width=\"40\" height=\"40\" \/><!-- [et_pb_line_break_holder] --> <\/a><!-- [et_pb_line_break_holder] --><\/li>\n<p><!-- [et_pb_line_break_holder] --><\/p>\n<li><!-- [et_pb_line_break_holder] --> <a href=\"https:\/\/www.youtube.com\/channel\/UCU8kCv9oZAJCNrP3KZmRgTQ\"><!-- [et_pb_line_break_holder] --> <img loading=\"lazy\" decoding=\"async\" class=\"lazy\" src=\"\/\/assets.manchester.ac.uk\/phase1\/templates\/images\/icon-youtube-50.png\" alt=\"YouTube channel for the PROTECT project.\" width=\"40\" height=\"40\" \/><!-- [et_pb_line_break_holder] --> <\/a><!-- [et_pb_line_break_holder] --><\/li>\n<p><!-- [et_pb_line_break_holder] --><\/ul>\n<p>[\/et_pb_code][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243;][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Effectively implementing strategies to curb transmission of SARS-CoV-2 (the virus that causes COVID-19) requires understanding who is contagious and when. Whilst viral load (VL) on upper respiratory swabs has commonly been used to infer contagiousness, measuring viral emissions may be more accurate to indicate the chance of onward transmission and identify likely routes. This paper, [&hellip;]<\/p>\n","protected":false},"author":4299,"featured_media":1986,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_exactmetrics_skip_tracking":false,"footnotes":""},"categories":[13,65],"tags":[33,129,29,16,128,40],"class_list":["post-3877","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-papers","category-theme-5-experimental-infection","tag-covid-19","tag-human-challenge","tag-protect","tag-transmission","tag-viral-load","tag-virus-transmission"],"_links":{"self":[{"href":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/wp-json\/wp\/v2\/posts\/3877","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/wp-json\/wp\/v2\/users\/4299"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/wp-json\/wp\/v2\/comments?post=3877"}],"version-history":[{"count":6,"href":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/wp-json\/wp\/v2\/posts\/3877\/revisions"}],"predecessor-version":[{"id":4140,"href":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/wp-json\/wp\/v2\/posts\/3877\/revisions\/4140"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/wp-json\/wp\/v2\/media\/1986"}],"wp:attachment":[{"href":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/wp-json\/wp\/v2\/media?parent=3877"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/wp-json\/wp\/v2\/categories?post=3877"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/covid19-national-project\/wp-json\/wp\/v2\/tags?post=3877"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}