{"id":1584,"date":"2019-11-14T12:47:09","date_gmt":"2019-11-14T12:47:09","guid":{"rendered":"https:\/\/sites.manchester.ac.uk\/foodallergens\/?page_id=1584"},"modified":"2020-04-07T09:38:58","modified_gmt":"2020-04-07T08:38:58","slug":"genetically-modified-foods-and-food-allergy","status":"publish","type":"page","link":"https:\/\/sites.manchester.ac.uk\/foodallergens\/allergy-facts\/genetically-modified-foods-and-food-allergy\/","title":{"rendered":"Genetically modified foods and food allergy"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; admin_label=&#8221;section&#8221; _builder_version=&#8221;3.0.47&#8243; global_module=&#8221;322&#8243;][et_pb_fullwidth_menu menu_id=&#8221;7&#8243; submenu_direction=&#8221;downwards&#8221; fullwidth_menu=&#8221;off&#8221; module_class=&#8221;main-navigation&#8221; _builder_version=&#8221;3.0.106&#8243; background_layout=&#8221;dark&#8221;][\/et_pb_fullwidth_menu][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.0.74&#8243; custom_padding=&#8221;||0px|&#8221; transparent_background=&#8221;off&#8221;][et_pb_row custom_padding=&#8221;||0px|&#8221; custom_margin=&#8221;||0px|&#8221; parallax_method_1=&#8221;off&#8221; module_class=&#8221;breadcrumbs-row&#8221; _builder_version=&#8221;3.0.47&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.0.47&#8243; parallax=&#8221;off&#8221; parallax_method=&#8221;off&#8221;][et_pb_text admin_label=&#8221;Breadcrumbs (do not remove)&#8221; module_class=&#8221;breadcrumbs&#8221; _builder_version=&#8221;3.0.87&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;left&#8221; custom_css_main_element=&#8221;border-bottom: 1px solid #ececed;&#8221; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221;]<\/p>\n<p>\n<span><span><a href=\"https:\/\/sites.manchester.ac.uk\/foodallergens\/\">Food Allergens<\/a><\/span><\/span><br \/>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; specialty=&#8221;on&#8221; parallax_method_1=&#8221;off&#8221; parallax_method_2=&#8221;off&#8221; _builder_version=&#8221;3.0.74&#8243; transparent_background=&#8221;off&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.0.47&#8243; parallax=&#8221;off&#8221; parallax__hover=&#8221;off&#8221; parallax_method=&#8221;off&#8221; parallax_method__hover=&#8221;off&#8221;][et_pb_sidebar area=&#8221;et_pb_widget_area_1&#8243; show_border=&#8221;off&#8221; admin_label=&#8221;Left Nav Sidebar&#8221; module_id=&#8221;left-nav-menu&#8221; _builder_version=&#8221;3.0.74&#8243; remove_border=&#8221;on&#8221;][\/et_pb_sidebar][\/et_pb_column][et_pb_column type=&#8221;2_3&#8243; specialty_columns=&#8221;2&#8243; _builder_version=&#8221;3.0.47&#8243; parallax=&#8221;off&#8221; parallax__hover=&#8221;off&#8221; parallax_method=&#8221;off&#8221; parallax_method__hover=&#8221;off&#8221;][et_pb_row_inner admin_label=&#8221;Row&#8221; _builder_version=&#8221;3.0.47&#8243;][et_pb_column_inner type=&#8221;4_4&#8243; saved_specialty_column_type=&#8221;2_3&#8243; _builder_version=&#8221;3.0.47&#8243; parallax=&#8221;off&#8221; parallax__hover=&#8221;off&#8221; parallax_method=&#8221;on&#8221; parallax_method__hover=&#8221;on&#8221;][et_pb_text _builder_version=&#8221;3.17.6&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;left&#8221; use_border_color=&#8221;off&#8221;]<\/p>\n<h1>Genetically modified foods and food allergy<\/h1>\n<p style=\"font-size: 1.692308em;line-height: 1.5;font-weight: 300;padding: 0 0 30px;color: #14516e\">Genetically modified (GM) foods have their DNA changed to increase resistance to damage and\/or to improve their nutritional value.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-1590\" src=\"https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-content\/uploads\/sites\/208\/2019\/11\/genetically-modified-food.jpg\" alt=\"Genetically modified food samples in test tubes\" width=\"396\" height=\"325\" srcset=\"https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-content\/uploads\/sites\/208\/2019\/11\/genetically-modified-food.jpg 396w, https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-content\/uploads\/sites\/208\/2019\/11\/genetically-modified-food-300x246.jpg 300w, https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-content\/uploads\/sites\/208\/2019\/11\/genetically-modified-food-150x123.jpg 150w, https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-content\/uploads\/sites\/208\/2019\/11\/genetically-modified-food-250x205.jpg 250w, https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-content\/uploads\/sites\/208\/2019\/11\/genetically-modified-food-350x287.jpg 350w\" sizes=\"(max-width: 396px) 100vw, 396px\" \/>Because the GM food may contain new proteins, their potential allergenicity must be assessed before the foods are available for consumption.<\/p>\n<p>In Europe, GM crops are tightly regulated and assessed for allergenicity by the European Food Safety Authority (EFSA), yet concerns over GM food safety still exist.<\/p>\n<p>There are two widely reported studies which demonstrate GM foods causing an allergic reaction.<\/p>\n<p>In the first one, human volunteers developed an allergic reaction during the skin prick testing to the modified soya bean (with transferred Brazil-nut protein to improve its nutritional value).<\/p>\n<p>This food was never approved, which demonstrated the effectiveness of the GM food allergenicity assessment in protecting public health. In the second study, a bean modified to increase its resistance to damage, caused an immune reaction in the lungs of mice.<\/p>\n<p>The allergenicity of GM foods currently available on the international market has been evaluated and, according to the World Health Organisation (WHO), these foods are not likely to be harmful to people.<\/p>\n<p>The EFSA and Codex Alimentarius Commission framework established by WHO and the Food and Agriculture Organisation (FAO) to protect consumer health, provide a framework for undertaking allergenicity assessment.<\/p>\n<p>[\/et_pb_text][et_pb_accordion _builder_version=&#8221;3.17.6&#8243; border_color_all=&#8221;#ffffff&#8221; use_border_color=&#8221;off&#8221;][et_pb_accordion_item title=&#8221;Further reading&#8221; open=&#8221;on&#8221; _builder_version=&#8221;3.17.6&#8243; title_text_shadow_horizontal_length=&#8221;0em&#8221; title_text_shadow_vertical_length=&#8221;0em&#8221; title_text_shadow_blur_strength=&#8221;0em&#8221; body_text_shadow_horizontal_length=&#8221;0em&#8221; body_text_shadow_vertical_length=&#8221;0em&#8221; body_text_shadow_blur_strength=&#8221;0em&#8221;]<\/p>\n<ul>\n<li>FAO\/WHO Food Standards. Codex Alimentarius. <a href=\"http:\/\/www.codexalimentarius.net\/\">Principles for the risk analysis of foods derived from modern biotechnology<\/a><\/li>\n<li>The EFSA Journal (2011) <a href=\"https:\/\/www.efsa.europa.eu\/en\/efsajournal\/pub\/2193\">Guidance document of the Scientific Panel on Genetically Modified Organisms for the risk assessment of genetically modified plants and derived food and feed<\/a><\/li>\n<li>Hanspeter, N., Nicholas, B. A., Josep, C., et al. (2017) <a href=\"https:\/\/www.efsa.europa.eu\/en\/efsajournal\/pub\/4862\">Guidance on allergenicity assessment of genetically modified plants<\/a><\/li>\n<li>Selb R, Wal JM, Moreno FJ, et al. (2017) <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28111299\">Assessment of endogenous allergenicity of genetically modified plants exemplified by soybean &#8211; Where do we stand?<\/a><\/li>\n<li>Fernandez A, Mills ENC, Koning F, Moreno FJ (2019) <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31005332\">Safety Assessment of Immune-Mediated Adverse Reactions to Novel Food Proteins<\/a><\/li>\n<li>Naegeli H, Birch AN, Casacuberta J, De Schrijver A, Gralak Mikolaj A, Guerche P, Jones H, Manachini B, Mess\u00e9an A, Nielsen EE, Nogu\u00e9 F, Robaglia C, Rostoks N, Sweet J, Tebbe C, Visioli F, Wal J-M, et al. (2017) EFSA Panel on Genetically Modified Organisms; <a href=\"https:\/\/efsa.onlinelibrary.wiley.com\/doi\/10.2903\/j.efsa.2017.4862\">Guidance on allergenicity assessment of genetically modified plants<\/a><\/li>\n<\/ul>\n<p>[\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Connect Title&#8221; module_class=&#8221;footer-section&#8221; _builder_version=&#8221;3.0.90&#8243; background_color=&#8221;#1d1d1d&#8221; custom_padding=&#8221;0px||0px|&#8221; global_module=&#8221;380&#8243;][et_pb_row parallax_method_1=&#8221;off&#8221; parallax_method_2=&#8221;off&#8221; parallax_method_3=&#8221;off&#8221; admin_label=&#8221;row&#8221; module_id=&#8221;footer-row&#8221; _builder_version=&#8221;3.0.89&#8243; locked=&#8221;off&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.0.47&#8243; parallax=&#8221;off&#8221; parallax_method=&#8221;off&#8221;][et_pb_text admin_label=&#8221;Contact Us Title&#8221; 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Because the GM food may contain new proteins, their potential allergenicity must be assessed before the foods are available for consumption. In Europe, GM crops are tightly regulated and [&hellip;]<\/p>\n","protected":false},"author":13,"featured_media":0,"parent":1499,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_exactmetrics_skip_tracking":false,"footnotes":""},"class_list":["post-1584","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-json\/wp\/v2\/pages\/1584","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-json\/wp\/v2\/comments?post=1584"}],"version-history":[{"count":10,"href":"https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-json\/wp\/v2\/pages\/1584\/revisions"}],"predecessor-version":[{"id":2014,"href":"https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-json\/wp\/v2\/pages\/1584\/revisions\/2014"}],"up":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-json\/wp\/v2\/pages\/1499"}],"wp:attachment":[{"href":"https:\/\/sites.manchester.ac.uk\/foodallergens\/wp-json\/wp\/v2\/media?parent=1584"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}