\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ use_custom_gutter=”on” gutter_width=”2″ specialty=”on” parallax_method_1=”off” parallax_method_2=”off” _builder_version=”3.0.74″ transparent_background=”off”][et_pb_column type=”1_3″ _builder_version=”3.0.47″ parallax__hover=”off” parallax_method__hover=”off” parallax=”off” parallax_method=”off”][et_pb_sidebar area=”et_pb_widget_area_1″ show_border=”off” admin_label=”Left Nav Sidebar” module_id=”left-nav-menu” _builder_version=”3.0.74″ remove_border=”on”][\/et_pb_sidebar][\/et_pb_column][et_pb_column type=”2_3″ specialty_columns=”2″ _builder_version=”3.0.47″ parallax__hover=”off” parallax_method__hover=”off” parallax=”off” parallax_method=”off”][et_pb_row_inner admin_label=”Row” _builder_version=”3.0.47″][et_pb_column_inner type=”4_4″ saved_specialty_column_type=”2_3″ _builder_version=”3.0.47″ parallax__hover=”off” parallax_method__hover=”on” parallax=”off” parallax_method=”on”][et_pb_text admin_label=”Text: Publication list” _builder_version=”3.17.6″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”left” use_border_color=”off”]<\/p>\n
Publications<\/h1>\n
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2021<\/h1>\n
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Marinopoulou, E., Biga, V., Sabherwal, N., Miller, A., Desai, J., Adamson, A.D., Papalopulu, N., 2021. HES1 protein oscillations are necessary for neural stem cells to exit from quiescence. iScience 24, 103198. https:\/\/doi.org\/10.1016\/j.isci.2021.103198<\/a><\/p>\n <\/p>\n Morris, E.L., Patton, A.P., Chesham, J.E., Crisp, A., Adamson, A., Hastings, M.H., 2021. Single-cell transcriptomics of suprachiasmatic nuclei reveal a Prokineticin-driven circadian network. EMBO J e108614. https:\/\/doi.org\/10.15252\/embj.2021108614<\/a><\/p>\n <\/p>\n Bennett, H., Aguilar-Martinez, E., Adamson, A.D., 2021. CRISPR-mediated knock-in in the mouse embryo using long single stranded DNA donors synthesised by biotinylated PCR. Methods 191, 3\u201314. https:\/\/doi.org\/10.1016\/j.ymeth.2020.10.012<\/a><\/p>\n <\/p>\n Biga, V., Hawley, J., Soto, X., Johns, E., Han, D., Bennett, H., Adamson, A.D., Kursawe, J., Glendinning, P., Manning, C.S., Papalopulu, N., 2021. A dynamic, spatially periodic, micro-pattern of HES5 underlies neurogenesis in the mouse spinal cord. Molecular Systems Biology 17, e9902. https:\/\/doi.org\/10.15252\/msb.20209902<\/a><\/p>\n <\/p>\n Gurumurthy, C.B., O\u2019Brien, A.R., Quadros, R.M., Adams, J., Alcaide, P., Ayabe, S., Ballard, J., Batra, S.K., Beauchamp, M.-C., Becker, K.A., Bernas, G., Brough, D., Carrillo-Salinas, F., Chan, W., Chen, H., Dawson, R., DeMambro, V., D\u2019Hont, J., Dibb, K., Eudy, J.D., Gan, L., Gao, J., Gonzales, A., Guntur, A., Guo, H., Harms, D.W., Harrington, A., Hentges, K.E., Humphreys, N., Imai, S., Ishii, H., Iwama, M., Jonasch, E., Karolak, M., Keavney, B., Khin, N.-C., Konno, M., Kotani, Y., Kunihiro, Y., Lakshmanan, I., Larochelle, C., Lawrence, C.B., Li, L., Lindner, V., Liu, X.-D., Lopez-Castejon, G., Loudon, A., Lowe, J., Jerome-Majeweska, L., Matsusaka, T., Miura, H., Miyasaka, Y., Morpurgo, B., Motyl, K., Nabeshima, Y., Nakade, K., Nakashiba, T., Nakashima, K., Obata, Y., Ogiwara, S., Ouellet, M., Oxburgh, L., Piltz, S., Pinz, I., Ponnusamy, M.P., Ray, D., Redder, R.J., Rosen, C.J., Ross, N., Ruhe, M.T., Ryzhova, L., Salvador, A.M., Alam, S.S., Sedlacek, R., Sharma, K., Smith, C., Staes, K., Starrs, L., Sugiyama, F., Takahashi, S., Tanaka, T., Trafford, A., Uno, Y., Vanhoutte, L., Vanrockeghem, F., Willis, B.J., Wright, C.S., Yamauchi, Y., Yi, X., Yoshimi, K., Zhang, X., Zhang, Y., Ohtsuka, M., Das, S., Garry, D.J., Hochepied, T., Thomas, P., Parker-Thornburg, J., Adamson, A.D., Yoshiki, A., Schmouth, J.-F., Golovko, A., Thompson, W.R., Lloyd, K.C.K., Wood, J.A., Cowan, M., Mashimo, T., Mizuno, S., Zhu, H., Kasparek, P., Liaw, L., Miano, J.M., Burgio, G., 2021. Response to correspondence on \u201cReproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation.\u201d Genome Biol 22, 1\u20134. https:\/\/doi.org\/10.1186\/s13059-021-02320-3<\/a><\/p>\n <\/p>\n Hunter, A.L., Pelekanou, C.E., Barron, N.J., Northeast, R.C., Grudzien, M., Adamson, A.D., Downton, P., Cornfield, T., Cunningham, P.S., Billaud, J.-N., Hodson, L., Loudon, A.S., Unwin, R.D., Iqbal, M., Ray, D.W., Bechtold, D.A., 2021. Adipocyte NR1D1 dictates adipose tissue expansion during obesity. eLife 10, e63324. https:\/\/doi.org\/10.7554\/eLife.63324<\/a><\/p>\n <\/p>\n McNamara, A.V., Awais, R., Momiji, H., Dunham, L., Featherstone, K., Harper, C.V., Adamson, A.D., Semprini, S., Jones, N.A., Spiller, D.G., Mullins, J.J., Finkenst\u00e4dt, B.F., Rand, D., White, M.R.H., Davis, J.R.E., 2021. Transcription factor Pit-1 affects transcriptional timing in the dual-promoter human prolactin gene. Endocrinology. https:\/\/doi.org\/10.1210\/endocr\/bqaa249<\/a><\/p>\n <\/p>\n Thieme, F., Henschel, L., Hammond, N.L., Ishorst, N., Hausen, J., Adamson, A.D., Biedermann, A., Bowes, J., Zieger, H.K., Maj, C., Kruse, T., Buness, A., Hoischen, A., Gilissen, C., Kreusch, T., J\u00e4ger, A., G\u00f6lz, L., Braumann, B., Aldhorae, K., Rojas-Martinez, A., Krawitz, P.M., Mangold, E., Dixon, M.J., Ludwig, K.U., 2021. Extending the allelic spectrum at noncoding risk loci of orofacial clefting. Hum Mutat 42, 1066\u20131078. https:\/\/doi.org\/10.1002\/humu.24219<\/a><\/p>\n <\/p>\n Preprints<\/i><\/p>\n <\/p>\n Bagnall, J.S., Koch, A.A., Smyllie, N.J., Begley, N., Adamson, A., Fribourgh, J.L., Spiller, D.G., Meng, Q.-J., Partch, C.L., Strimmer, K., House, T.A., Hastings, M.H., Loudon, A.S.I., 2021. Quantification of circadian interactions and protein abundance defines a mechanism for operational stability of the circadian clock. https:\/\/doi.org\/10.1101\/2021.08.27.456017<\/a><\/p>\n <\/p>\n Lee, B., Hoyle, C., Green, J.P., Wellens, R., Martin-Sanchez, F., Williams, D., Seoane, P.I., Bennett, H., Adamson, A., Lopez-Castejon, G., Lowe, M., Brough, D., 2021. NLRP3 activation in response to disrupted endocytic traffic. <\/span>https:\/\/doi.org\/10.1101\/2021.09.15.460426<\/span><\/a><\/span><\/span><\/p>\n <\/p>\n Jayadev, R., Morais, M.R., Ellingford, J.M., Srinivasan, S., Naylor, R.W., Lawless, C., Li, A.S., Ingham, J.F., Hastie, E., Chi, Q., Fresquet, M., Koudis, N.-M., Thomas, H.B., O\u2019Keefe, R.T., Williams, E., Adamson, A., Stuart, H.M., Banka, S., Smedley, D., Consortium, G.E.R., Sherwood, D.R., Lennon, R., 2021. A basement membrane discovery pipeline uncovers network complexity, new regulators, and human disease associations. https:\/\/doi.org\/10.1101\/2021.10.25.465762<\/a><\/p>\n <\/p>\n Atherton, P., Konstantinou, R., Neo, S.P., Wang, E., Balloi, E., Ptushkina, M., Bennett, H., Clark, K., Gunaratne, J., Critchley, D., Barsukov, I., Manser, E., Ballestrem, C., 2021. Tensin3 interaction with talin drives formation of fibronectin-associated fibrillar adhesions. https:\/\/doi.org\/10.1101\/2021.07.16.452612<\/a><\/p>\n <\/p>\n Gemperle, J., Harrison, T., Flett, C., Adamson, A., Caswell, P., 2021. DExCon, DExogron, LUXon: on-demand expression control of endogenous genes reveals differential dynamics of Rab11 family members. https:\/\/doi.org\/10.1101\/2021.12.03.471086<\/a><\/span><\/p>\n <\/p>\n Stables, J., Green, E.K., Sehgal, A., Patkar, O., Keshvari, S., Taylor, I., Ashcroft, M.E., Grabert, K., Wollscheid-Lengeling, E., Szymkowiak, S., McColl, B.W., Adamson, A., Humphreys, N.E., Mueller, W., Starobova, H., Vetter, I., Shabestari, S.K., Blurton-Jones, M.M., Summers, K.M., Irvine, K.M., Pridans, C., Hume, D.A., 2021. A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant-negative impact on CSF1R signaling. https:\/\/doi.org\/10.1101\/2021.09.29.462493<\/a><\/p>\n <\/p>\n \u00a0<\/p>\n <\/p>\n <\/p>\n Al Kindi, A., Williams, H., Matsuda, K., Alkahtani, A.M., Saville, C., Bennett, H., Alshammari, Y., Tan, S.Y., O\u2019Neill, C., Tanaka, A., Matsuda, H., Arkwright, P.D., Pennock, J.L., 2021. Staphylococcus aureus second immunoglobulin-binding protein drives atopic dermatitis via IL-33. J Allergy Clin Immunol 147, 1354-1368.e3. https:\/\/doi.org\/10.1016\/j.jaci.2020.09.023<\/a><\/p>\n <\/p>\n Baxter, M., Voronkov, M., Poolman, T., Galli, G., Pinali, C., Goosey, L., Knight, A., Krakowiak, K., Maidstone, R., Iqbal, M., Zi, M., Prehar, S., Cartwright, E.J., Gibbs, J., Matthews, L.C., Adamson, A.D., Humphreys, N.E., Rebelo-Guiomar, P., Minczuk, M., Bechtold, D.A., Loudon, A., Ray, D., 2020. Cardiac mitochondrial function depends on BUD23 mediated ribosome programming. Elife 9. https:\/\/doi.org\/10.7554\/eLife.50705<\/a><\/p>\n <\/p>\n Chang, J., Garva, R., Pickard, A., Yeung, C.-Y.C., Mallikarjun, V., Swift, J., Holmes, D.F., Calverley, B., Lu, Y., Adamson, A., Raymond-Hayling, H., Jensen, O., Shearer, T., Meng, Q.J., Kadler, K.E., 2020. Circadian control of the secretory pathway maintains collagen homeostasis. Nat. Cell Biol. 22, 74\u201386. https:\/\/doi.org\/10.1038\/s41556-019-0441-z<\/a><\/p>\n <\/p>\n Evans, E.L., Povstyan, O.V., De Vecchis, D., Macrae, F., Lichtenstein, L., Futers, T.S., Parsonage, G., Humphreys, N.E., Adamson, A., Kalli, A.C., Ludlow, M.J., Beech, D.J., 2020. RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of dehydrated hereditary stomatocytosis. Blood 136, 140\u2013144. https:\/\/doi.org\/10.1182\/blood.2019004174<\/a><\/p>\n <\/p>\n Grabert, K., Sehgal, A., Irvine, K.M., Wollscheid-Lengeling, E., Ozdemir, D.D., Stables, J., Luke, G.A., Ryan, M.D., Adamson, A., Humphreys, N.E., Sandrock, C.J., Rojo, R., Verkasalo, V.A., Mueller, W., Hohenstein, P., Pettit, A.R., Pridans, C., Hume, D.A., 2020. A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System. The Journal of Immunology. https:\/\/doi.org\/10.4049\/jimmunol.2000835<\/a><\/p>\n <\/p>\n Green, J.P., Swanton, T., Morris, L.V., El-Sharkawy, L.Y., Cook, J., Yu, S., Beswick, J., Adamson, A.D., Humphreys, N.E., Bryce, R., Freeman, S., Lawrence, C., Brough, D., 2020. LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation. eLife 9, e59704. https:\/\/doi.org\/10.7554\/eLife.59704<\/a><\/p>\n <\/p>\n Hunter, A.L., Pelekanou, C.E., Adamson, A., Downton, P., Barron, N.J., Cornfield, T., Poolman, T.M., Humphreys, N., Cunningham, P.S., Hodson, L., Loudon, A.S.I., Iqbal, M., Bechtold, D.A., Ray, D.W., 2020a. Nuclear receptor REVERB\u03b1 is a state-dependent regulator of liver energy metabolism. PNAS. https:\/\/doi.org\/10.1073\/pnas.2005330117<\/a><\/p>\n <\/p>\n Pinteaux, E., Abdulaal, W.H., Mufazalov, I.A., Humphreys, N.E., Simonsen-Jackson, M., Francis, S., M\u00fcller, W., Waisman, A., 2020. Cell-specific conditional deletion of interleukin-1 (IL-1) ligands and its receptors: a new toolbox to study the role of IL-1 in health and disease. J Mol Med (Berl) 98, 923\u2013930. https:\/\/doi.org\/10.1007\/s00109-020-01928-5<\/a><\/p>\n <\/p>\n Ray-Jones, H., Duffus, K., McGovern, A., Martin, P., Shi, C., Hankinson, J., Gough, O., Yarwood, A., Morris, A.P., Adamson, A., Taylor, C., Ding, J., Gaddi, V.P., Fu, Y., Gaffney, P., Orozco, G., Warren, R.B., Eyre, S., 2020. Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31. BMC Biol. 18, 47. https:\/\/doi.org\/10.1186\/s12915-020-00779-3<\/a><\/p>\n <\/p>\n Yang, J., McGovern, A., Martin, P., Duffus, K., Ge, X., Zarrineh, P., Morris, A.P., Adamson, A., Fraser, P., Rattray, M., Eyre, S., 2020. Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis. Nat Commun 11, 4402. https:\/\/doi.org\/10.1038\/s41467-020-18180-7<\/a><\/p>\n <\/p>\n Yang, N., Smyllie, N.J., Morris, H., Gon\u00e7alves, C.F., Dudek, M., Pathiranage, D.R.J., Chesham, J.E., Adamson, A., Spiller, D.G., Zindy, E., Bagnall, J., Humphreys, N., Hoyland, J., Loudon, A.S.I., Hastings, M.H., Meng, Q.-J., 2020. Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator. PLoS Genet. 16, e1008729. https:\/\/doi.org\/10.1371\/journal.pgen.1008729<\/a><\/p>\n <\/p>\n <\/p>\n Preprints<\/i><\/p>\n <\/p>\n Borland, S.J., Facchi, C., Behnsen, J., Adamson, A., Humphreys, N.E., Withers, P.J., Sherratt, M.J., Francis, S.E., Brennan, K., Ashton, N., Canfield, A.E., 2020. Loss of PKC\u03b1 increases arterial medial calcification in a uremic mouse model of chronic kidney disease. bioRxiv 2020.05.20.097642. https:\/\/doi.org\/10.1101\/2020.05.20.097642<\/a><\/p>\n <\/p>\n \u00a0<\/p>\n <\/p>\n <\/p>\n Bageghni, S.A., Hemmings, K.E., Yuldasheva, N.Y., Maqbool, A., Gamboa-Esteves, F.O., Humphreys, N.E., Jackson, M.S., Denton, C.P., Francis, S., Porter, K.E., Ainscough, J.F., Pinteaux, E., Drinkhill, M.J., Turner, N.A., 2019. Fibroblast-specific deletion of interleukin-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction. JCI Insight 5. https:\/\/doi.org\/10.1172\/jci.insight.125074<\/a><\/p>\n <\/p>\n Binder, P., Wang, S., Radu, M., Zin, M., Collins, L., Khan, S., Li, Y., Sekeres, K., Humphreys, N., Swanton, E., Reid, A., Pu, F., Oceandy, D., Guan, K., Hille, S.S., Frey, N., M\u00fcller, O.J., Cartwright, E.J., Chernoff, J., Wang, X., Liu, W., 2019. Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response. Circ. Res. 124, 696\u2013711. https:\/\/doi.org\/10.1161\/CIRCRESAHA.118.312829<\/a><\/p>\n <\/p>\n Birket, M.J., Raibaud, S., Lettieri, M., Adamson, A.D., Letang, V., Cervello, P., Redon, N., Ret, G., Viale, S., Wang, B., Biton, B., Guillemot, J.-C., Mikol, V., Leonard, J.P., Hanley, N.A., Orsini, C., Itier, J.-M., 2019. A Human Stem Cell Model of Fabry Disease Implicates LIMP-2 Accumulation in Cardiomyocyte Pathology. Stem Cell Reports 13, 380\u2013393. https:\/\/doi.org\/10.1016\/j.stemcr.2019.07.004<\/a><\/p>\n <\/p>\n Gurumurthy, C.B., O\u2019Brien, A.R., Quadros, R.M., Adams, J., Alcaide, P., Ayabe, S., Ballard, J., Batra, S.K., Beauchamp, M.-C., Becker, K.A., Bernas, G., Brough, D., Carrillo-Salinas, F., Chan, W., Chen, H., Dawson, R., DeMambro, V., D\u2019Hont, J., Dibb, K.M., Eudy, J.D., Gan, L., Gao, J., Gonzales, A., Guntur, A.R., Guo, H., Harms, D.W., Harrington, A., Hentges, K.E., Humphreys, N., Imai, S., Ishii, H., Iwama, M., Jonasch, E., Karolak, M., Keavney, B., Khin, N.-C., Konno, M., Kotani, Y., Kunihiro, Y., Lakshmanan, I., Larochelle, C., Lawrence, C.B., Li, L., Lindner, V., Liu, X.-D., Lopez-Castejon, G., Loudon, A., Lowe, J., Jerome-Majewska, L.A., Matsusaka, T., Miura, H., Miyasaka, Y., Morpurgo, B., Motyl, K., Nabeshima, Y.-I., Nakade, K., Nakashiba, T., Nakashima, K., Obata, Y., Ogiwara, S., Ouellet, M., Oxburgh, L., Piltz, S., Pinz, I., Ponnusamy, M.P., Ray, D., Redder, R.J., Rosen, C.J., Ross, N., Ruhe, M.T., Ryzhova, L., Salvador, A.M., Alam, S.S., Sedlacek, R., Sharma, K., Smith, C., Staes, K., Starrs, L., Sugiyama, F., Takahashi, S., Tanaka, T., Trafford, A.W., Uno, Y., Vanhoutte, L., Vanrockeghem, F., Willis, B.J., Wright, C.S., Yamauchi, Y., Yi, X., Yoshimi, K., Zhang, X., Zhang, Y., Ohtsuka, M., Das, S., Garry, D.J., Hochepied, T., Thomas, P., Parker-Thornburg, J., Adamson, A.D., Yoshiki, A., Schmouth, J.-F., Golovko, A., Thompson, W.R., Lloyd, K.C.K., Wood, J.A., Cowan, M., Mashimo, T., Mizuno, S., Zhu, H., Kasparek, P., Liaw, L., Miano, J.M., Burgio, G., 2019. Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation. Genome Biol. 20, 171. https:\/\/doi.org\/10.1186\/s13059-019-1776-2<\/a><\/p>\n <\/p>\n Minshawi, F., White, M.R.H., Muller, W., Humphreys, N., Jackson, D., Campbell, B.J., Adamson, A., Papoutsopoulou, S., 2019. Human TNF-Luc reporter mouse: A new model to quantify inflammatory responses. Sci Rep 9, 193. https:\/\/doi.org\/10.1038\/s41598-018-36969-x<\/a><\/p>\n <\/p>\n Sefton, C., Davies, A., Allen, T.-J., Wray, J.R., Shoop, R., Adamson, A., Humphreys, N., Coll, A.P., White, A., Harno, E., 2019. Metabolic Abnormalities of Chronic High-Dose Glucocorticoids Are Not Mediated by Hypothalamic AgRP in Male Mice. Endocrinology 160, 964\u2013978. https:\/\/doi.org\/10.1210\/en.2019-00018<\/a><\/p>\n <\/p>\n Wray, J.R., Davies, A., Sefton, C., Allen, T.-J., Adamson, A., Chapman, P., Lam, B.Y.H., Yeo, G.S.H., Coll, A.P., Harno, E., White, A., 2019. Global transcriptomic analysis of the arcuate nucleus following chronic glucocorticoid treatment. Mol Metab 26, 5\u201317. https:\/\/doi.org\/10.1016\/j.molmet.2019.05.008<\/a><\/p>\n <\/p>\n Preprints<\/i><\/p>\n <\/p>\n Summers, K.M., Pridans, C., Wollscheid-Lengeling, E., Grabert, K., Adamson, A., Humphreys, N.E., Irvine, K.M., Hume, D.A., 2019. Complex deletion and proximal reinsertion of a 150bp regulatory sequence in the mouse Csf1r promoter mediated by CRISPR-Cas9. bioRxiv 872200. https:\/\/doi.org\/10.1101\/872200<\/a><\/p>\n <\/p>\n \u00a0<\/p>\n <\/p>\n <\/p>\n Bagnall, J., Boddington, C., England, H., Brignall, R., Downton, P., Alsoufi, Z., Boyd, J., Rowe, W., Bennett, A., Walker, C., Adamson, A., Patel, N.M.X., O\u2019Cualain, R., Schmidt, L., Spiller, D.G., Jackson, D.A., M\u00fcller, W., Muldoon, M., White, M.R.H., Paszek, P., 2018. Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation. Sci Signal 11. https:\/\/doi.org\/10.1126\/scisignal.aaf3998<\/a>\u00a0 <\/span><\/p>\n <\/p>\n Harper, C.V., Woodcock, D.J., Lam, C., Garcia-Albornoz, M., Adamson, A., Ashall, L., Rowe, W., Downton, P., Schmidt, L., West, S., Spiller, D.G., Rand, D.A., White, M.R.H., 2018. Temperature regulates NF-\u03baB dynamics and function through timing of A20 transcription. Proc. Natl. Acad. Sci. U.S.A. 115, E5243\u2013E5249. https:\/\/doi.org\/10.1073\/pnas.1803609115<\/a><\/p>\n <\/p>\n Mularczyk, E.J., Singh, M., Godwin, A.R.F., Galli, F., Humphreys, N., Adamson, A.D., Mironov, A., Cain, S.A., Sengle, G., Boot-Handford, R.P., Cossu, G., Kielty, C.M., Baldock, C., 2018. ADAMTS10-mediated tissue disruption in Weill-Marchesani syndrome. Hum. Mol. Genet. 27, 3675\u20133687. https:\/\/doi.org\/10.1093\/hmg\/ddy276<\/a><\/p>\n <\/p>\n Roostalu, U., Aldeiri, B., Albertini, A., Humphreys, N., Simonsen-Jackson, M., Wong, J.K.F., Cossu, G., 2018. Distinct Cellular Mechanisms Underlie Smooth Muscle Turnover in Vascular Development and Repair. Circ. Res. 122, 267\u2013281. https:\/\/doi.org\/10.1161\/CIRCRESAHA.117.312111<\/a> <\/i><\/p>\n <\/p>\n Preprints<\/i><\/p>\n <\/p>\n Pickard, A., Adamson, A., Lu, Y., Chang, J., Garva, R., Hodson, N., Kadler, K.E., 2018. Collagen assembly and turnover imaged with a CRISPR-Cas9 engineered Dendra2 tag (preprint). Cell Biology. https:\/\/doi.org\/10.1101\/331496<\/a><\/p>\n <\/p>\n \u00a0<\/p>\n <\/p>\n <\/p>\n Daniels, M.J.D., Adamson, A.D., Humphreys, N., Brough, D., 2017. CRISPR\/Cas9 mediated mutation of mouse IL-1\u03b1 nuclear localisation sequence abolishes expression. Scientific Reports 7, 17077. https:\/\/doi.org\/10.1038\/s41598-017-17387-x<\/a><\/p>\n <\/p>\n Dudek, M., Yang, N., Ruckshanthi, J.P., Williams, J., Borysiewicz, E., Wang, P., Adamson, A., Li, J., Bateman, J.F., White, M.R., Boot-Handford, R.P., Hoyland, J.A., Meng, Q.-J., 2017. The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration. Ann. Rheum. Dis. 76, 576\u2013584. https:\/\/doi.org\/10.1136\/annrheumdis-2016-209428<\/a><\/p>\n <\/p>\n <\/p>\n Adamson, A., Boddington, C., Downton, P., Rowe, W., Bagnall, J., Lam, C., Maya-Mendoza, A., Schmidt, L., Harper, C.V., Spiller, D.G., Rand, D.A., Jackson, D.A., White, M.R.H., Paszek, P., 2016. Signal transduction controls heterogeneous NF-\u03baB dynamics and target gene expression through cytokine-specific refractory states. Nat Commun 7, 12057. https:\/\/doi.org\/10.1038\/ncomms12057<\/a><\/p>\n <\/p>\n Ankers, J.M., Awais, R., Jones, N.A., Boyd, J., Ryan, S., Adamson, A.D., Harper, C.V., Bridge, L., Spiller, D.G., Jackson, D.A., Paszek, P., S\u00e9e, V., White, M.R., 2016. Dynamic NF-\u03baB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation. Elife 5. https:\/\/doi.org\/10.7554\/eLife.10473<\/a><\/p>\n <\/p>\n McNamara, A.V., Adamson, A.D., Dunham, L.S.S., Semprini, S., Spiller, D.G., McNeilly, A.S., Mullins, J.J., Davis, J.R.E., White, M.R.H., 2016. Role of Estrogen Response Element in the Human Prolactin Gene: Transcriptional Response and Timing. Mol. Endocrinol. 30, 189\u2013200. https:\/\/doi.org\/10.1210\/me.2015-1186<\/a><\/p>\n <\/p>\n \u00a0<\/p>\n <\/p>\n <\/p>\n Guo, B., Yang, N., Borysiewicz, E., Dudek, M., Williams, J.L., Li, J., Maywood, E.S., Adamson, A., Hastings, M.H., Bateman, J.F., White, M.R.H., Boot-Handford, R.P., Meng, Q.J., 2015. Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NF\u043aB-dependent pathway. Osteoarthr. 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