{"id":1423,"date":"2020-06-29T14:54:26","date_gmt":"2020-06-29T13:54:26","guid":{"rendered":"https:\/\/sites.manchester.ac.uk\/ifaam\/?page_id=1423"},"modified":"2021-02-11T14:00:55","modified_gmt":"2021-02-11T14:00:55","slug":"home","status":"publish","type":"page","link":"https:\/\/sites.manchester.ac.uk\/ifaam\/","title":{"rendered":"Home"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; fullwidth=&#8221;on&#8221; next_background_color=&#8221;#000000&#8243; global_module=&#8221;322&#8243;][et_pb_fullwidth_menu global_parent=&#8221;322&#8243; _builder_version=&#8221;3.0.106&#8243; menu_id=&#8221;7&#8243; submenu_direction=&#8221;downwards&#8221; fullwidth_menu=&#8221;off&#8221; background_layout=&#8221;dark&#8221; module_class=&#8221;main-navigation&#8221; \/][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; specialty=&#8221;off&#8221; prev_background_color=&#8221;#000000&#8243; next_background_color=&#8221;#000000&#8243;][et_pb_fullwidth_slider show_arrows=&#8221;off&#8221; 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child_filter_blur=&#8221;0px&#8221; child_mix_blend_mode=&#8221;normal&#8221; background_layout=&#8221;dark&#8221; text_shadow_style=&#8221;none&#8221; header_text_shadow_style=&#8221;none&#8221; body_text_shadow_style=&#8221;none&#8221; custom_button=&#8221;on&#8221; button_bg_color=&#8221;#27a2db&#8221; button_bg_use_color_gradient=&#8221;off&#8221; button_bg_color_gradient_overlays_image=&#8221;off&#8221; button_border_color=&#8221;#27a2db&#8221; button_use_icon=&#8221;on&#8221; button_on_hover=&#8221;on&#8221; button_text_shadow_style=&#8221;none&#8221; box_shadow_style_button=&#8221;none&#8221; hover_transition_duration=&#8221;300ms&#8221; hover_transition_delay=&#8221;0ms&#8221; hover_transition_speed_curve=&#8221;ease&#8221; text_shadow_horizontal_length=&#8221;0em&#8221; text_shadow_vertical_length=&#8221;0em&#8221; text_shadow_blur_strength=&#8221;0em&#8221; header_text_shadow_horizontal_length=&#8221;0em&#8221; header_text_shadow_vertical_length=&#8221;0em&#8221; header_text_shadow_blur_strength=&#8221;0em&#8221; body_text_shadow_horizontal_length=&#8221;0em&#8221; body_text_shadow_vertical_length=&#8221;0em&#8221; body_text_shadow_blur_strength=&#8221;0em&#8221; button_text_shadow_horizontal_length=&#8221;0em&#8221; button_text_shadow_vertical_length=&#8221;0em&#8221; button_text_shadow_blur_strength=&#8221;0em&#8221;]<\/p>\n<p>Integrated Approaches to Food Allergen and Allergy Management<\/p>\n<p>[\/et_pb_slide][\/et_pb_fullwidth_slider][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; fullwidth=&#8221;off&#8221; specialty=&#8221;off&#8221; prev_background_color=&#8221;#000000&#8243; next_background_color=&#8221;#1d1d1d&#8221;][et_pb_row][et_pb_column type=&#8221;4_4&#8243;][et_pb_text admin_label=&#8221;Spacer&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p>\n&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row][et_pb_column type=&#8221;1_2&#8243;][et_pb_text admin_label=&#8221;Into left&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p class=\"subHeading\" style=\"color: #14516e\">Integrated Approaches to Food Allergen and Allergy Management (iFAAM) was an EU-funded project to develop evidence-based approaches in order to prevent and manage food allergies, and reduce the burden borne by food-allergic patients.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243;][et_pb_text admin_label=&#8221;Intro right&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p>With 43 partner organisations from 19 countries &#8211; 14 EU member states plus Iceland, Switzerland, Turkey, the US and Australia &#8211; iFAAM built on the outputs of the preceding project, EuroPrevall.<\/p>\n<p>It explored the following interrelated topics:<\/p>\n<ul>\n<li><a href=\"https:\/\/sites.manchester.ac.uk\/ifaam\/early-life-nutrition-and-allergy\/\">early life nutrition and allergy<\/a><\/li>\n<li><a href=\"https:\/\/sites.manchester.ac.uk\/ifaam\/risk-factors-and-severity\/\">risk factors and severity<\/a><\/li>\n<li><a href=\"https:\/\/sites.manchester.ac.uk\/ifaam\/risk-models\/\">risk models for managing allergens in food<\/a><\/li>\n<li>analysis of allergens in food<\/li>\n<\/ul>\n<p>The tools and data from the project have been used to create a food allergen and allergy management knowledge base made up of the following tools.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row][et_pb_column type=&#8221;4_4&#8243;][et_pb_text admin_label=&#8221;Spacer&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p>\n&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][et_pb_divider _builder_version=&#8221;3.17.6&#8243; \/][\/et_pb_column][\/et_pb_row][et_pb_row][et_pb_column type=&#8221;4_4&#8243;][et_pb_text _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<h2 id=\"tool\" style=\"color: #27a2db;font-size: 2.615385em\">Food allergen management tools<\/h2>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row][et_pb_column type=&#8221;1_2&#8243;][et_pb_text admin_label=&#8221;Management tool left&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p class=\"subHeading\" style=\"color: #14516e\">Tools and approaches have been developed for the food industry, and particularly to support small and medium-sized businesses in allergen management.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243;][et_pb_accordion _builder_version=&#8221;3.17.6&#8243;][et_pb_accordion_item _builder_version=&#8221;3.17.6&#8243; title=&#8221;Allergen tracking tool&#8221;]<\/p>\n<p>An important aspect of managing allergens in foods is to understand how allergens may enter food ingredients across the supply chain, and then how food manufacturing processes may result in allergen contamination.<\/p>\n<p>We have developed an allergen tracking tool that can estimate the probability of unintended allergen presence by identifying this presence and then undertaking a vulnerability assessment based on the production steps.<\/p>\n<p>An extension of the tool covers a vulnerability analysis of the supply chain.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item _builder_version=&#8221;3.17.6&#8243; title=&#8221;Tier 1 risk assessment&#8221;]<\/p>\n<p>The concentration of unintentional allergen (in mg total protein of the allergenic food) present in a food product can be determined in one of two ways:<\/p>\n<ul>\n<li>estimating the level of unintended allergen presence using information such as the allergen content in the preceding recipe, and estimating the carryover into the next production batch, or<\/li>\n<li>analysing the final product and\/or samples taken at intermediate steps in the manufacturing process.<\/li>\n<\/ul>\n<p><em>[Tier 1 model to go here]<\/em><\/p>\n<p>If the Tier 1 tool shows that the potential allergen exposure in a given product is above the reference dose, mitigation measures have to be employed and the cycle repeated.<\/p>\n<p>If the problem persists, a Tier 2 risk assessment (see below) should be applied and, if mitigation proves insufficient, a precautionary allergen label applied.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item _builder_version=&#8221;3.17.6&#8243; title=&#8221;Tier 2 risk assessment&#8221;]<\/p>\n<p>Probabilistic risk assessment approaches for food allergy have been developed based on mathematical modelling.<\/p>\n<p>A comparison of different probabilistic models showed that they provide a consistent risk estimate, and therefore formed a consensus approach.<\/p>\n<h2>Further reading<\/h2>\n<ul>\n<li>Spanjersberg M Q, Kruizinga A G, Rennen M A, Houben G F (2007) Risk Assessment and Food Allergy: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16979276\/\">The Probabilistic Model Applied to Allergens<\/a><\/li>\n<li>Rimbaud L, Heraud F, La Vieille S, Leblanc J C, Crepet A (2010) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20002890\/\">Quantitative Risk Assessment Relating to Adventitious Presence of Allergens in Food: A Probabilistic Model Applied to Peanut in Chocolate<\/a><\/li>\n<\/ul>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item _builder_version=&#8221;3.17.6&#8243; title=&#8221;Risk mitigation matrix&#8221;]<\/p>\n<p>The risk mitigation matrix summarises the risk management measures taken from literature, guidelines and practice.<\/p>\n<p>Measures are organised by location in the process or facility. An indication of cost and efficacy of the measure has been added to allow the best choice based on needs and resources.<\/p>\n<p>[mitigation matrix to go here]<\/p>\n<p>[\/et_pb_accordion_item][\/et_pb_accordion][et_pb_text admin_label=&#8221;Management tool right&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p>\nPlease <a href=\"#contact\">contact us<\/a> if you have any questions about the tools.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row][et_pb_column type=&#8221;4_4&#8243;][et_pb_text admin_label=&#8221;Spacer&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p>\n&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][et_pb_image _builder_version=&#8221;3.17.6&#8243; src=&#8221;https:\/\/sites.manchester.ac.uk\/ifaam\/wp-content\/uploads\/sites\/261\/2020\/07\/aller2.jpg&#8221; \/][\/et_pb_column][\/et_pb_row][et_pb_row][et_pb_column type=&#8221;4_4&#8243;][et_pb_text admin_label=&#8221;Clinical study data Title&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<h1>Clinical study data<\/h1>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row][et_pb_column type=&#8221;1_2&#8243;][et_pb_text admin_label=&#8221;C data left&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p class=\"subHeading\" style=\"color: #14516e\">Clinical data from the iFAAM and EuroPrevall studies is also available.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243;][et_pb_text admin_label=&#8221;C data right&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p>Please contact us to request access to this data. The iFAAM-EuroPrevall data access management committee will then review your request.\u00a0<\/p>\n<p>Email:\u00a0<a href=\"mailto:pafastudy@manchester.ac.uk\">pafastudy@manchester.ac.uk<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row][et_pb_column type=&#8221;4_4&#8243;][et_pb_text admin_label=&#8221;Spacer&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p>\n&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][et_pb_divider _builder_version=&#8221;3.17.6&#8243; \/][\/et_pb_column][\/et_pb_row][et_pb_row][et_pb_column type=&#8221;4_4&#8243;][et_pb_text admin_label=&#8221;Contact us Title&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<h2 id=\"contact\" style=\"color: #27a2db;font-size: 2.615385em\">Contact us<\/h2>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row][et_pb_column type=&#8221;1_2&#8243;][et_pb_text admin_label=&#8221;Contact us left&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p class=\"subHeading\" style=\"color: #14516e\">Get in touch if you have any questions about the iFAAM project or outputs.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243;][et_pb_text admin_label=&#8221;Contact us right&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p>Email:\u00a0<a href=\"mailto:pafastudy@manchester.ac.uk\">pafastudy@manchester.ac.uk<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; admin_label=&#8221;Connect Title&#8221; custom_padding=&#8221;0px||0px|&#8221; _builder_version=&#8221;3.0.90&#8243; background_color=&#8221;#1d1d1d&#8221; module_class=&#8221;footer-section&#8221; prev_background_color=&#8221;#ffffff&#8221; global_module=&#8221;380&#8243;][et_pb_row admin_label=&#8221;row&#8221; global_parent=&#8221;380&#8243; locked=&#8221;off&#8221; allow_player_pause=&#8221;off&#8221; parallax=&#8221;off&#8221; parallax_method=&#8221;on&#8221; parallax_1=&#8221;off&#8221; parallax_method_1=&#8221;off&#8221; parallax_2=&#8221;off&#8221; parallax_method_2=&#8221;off&#8221; parallax_3=&#8221;off&#8221; parallax_method_3=&#8221;off&#8221; make_fullwidth=&#8221;off&#8221; use_custom_width=&#8221;off&#8221; width_unit=&#8221;on&#8221; use_custom_gutter=&#8221;off&#8221; make_equal=&#8221;off&#8221; module_id=&#8221;footer-row&#8221; _builder_version=&#8221;3.0.89&#8243;][et_pb_column type=&#8221;1_3&#8243;][et_pb_text admin_label=&#8221;Contact Us Title&#8221; global_parent=&#8221;380&#8243; background_layout=&#8221;dark&#8221; text_text_color=&#8221;#ffffff&#8221; parent_locked=&#8221;off&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;]<\/p>\n<h4>Contact Us<\/h4>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Contact Us&#8221; global_parent=&#8221;380&#8243; text_text_color=&#8221;#aaaaaa&#8221; parent_locked=&#8221;off&#8221; background_layout=&#8221;light&#8221; text_orientation=&#8221;left&#8221; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; module_class=&#8221;contact-us&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;]<\/p>\n<p>+44 (0) 161 306 6000<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243;][et_pb_text admin_label=&#8221;Find Us Title&#8221; global_parent=&#8221;380&#8243; background_layout=&#8221;dark&#8221; text_text_color=&#8221;#ffffff&#8221; parent_locked=&#8221;off&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;]<\/p>\n<h4>Find Us<\/h4>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Address&#8221; global_parent=&#8221;380&#8243; background_layout=&#8221;dark&#8221; text_orientation=&#8221;left&#8221; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; module_id=&#8221;address&#8221; parent_locked=&#8221;off&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;]<\/p>\n<p><a href=\"http:\/\/www.manchester.ac.uk\/discover\/maps\/interactive-map\/\">The University of Manchester<br \/>Oxford Rd<br \/>Manchester<br \/>M13 9PL<br \/>UK<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243;][et_pb_text admin_label=&#8221;Connect Title&#8221; 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&nbsp; <div class=\"et_pb_row et_pb_row_1 et_pb_row_empty\">\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div> Integrated Approaches to Food Allergen and Allergy Management (iFAAM) was an EU-funded project to develop evidence-based approaches in order to prevent and manage food allergies, and reduce the burden borne by food-allergic patients. With 43 partner organisations from 19 countries &#8211; 14 EU [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_exactmetrics_skip_tracking":false,"footnotes":""},"class_list":["post-1423","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.manchester.ac.uk\/ifaam\/wp-json\/wp\/v2\/pages\/1423","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.manchester.ac.uk\/ifaam\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.manchester.ac.uk\/ifaam\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/ifaam\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/ifaam\/wp-json\/wp\/v2\/comments?post=1423"}],"version-history":[{"count":37,"href":"https:\/\/sites.manchester.ac.uk\/ifaam\/wp-json\/wp\/v2\/pages\/1423\/revisions"}],"predecessor-version":[{"id":1507,"href":"https:\/\/sites.manchester.ac.uk\/ifaam\/wp-json\/wp\/v2\/pages\/1423\/revisions\/1507"}],"wp:attachment":[{"href":"https:\/\/sites.manchester.ac.uk\/ifaam\/wp-json\/wp\/v2\/media?parent=1423"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}