Radiotracers

Below is the extensive list of radiotracers we can produce at WMIC, which are applicable for research in the neurosciences, dementia, oncology and musculoskeletal fields. We have contracts Qualified Persons (QP) who can release tracers for use as IMPs in Clinical Trials.

Tracer Application Status
[15O] Water Blood flow measurement GMP
[15O] Carbon monoxide Blood volume measurement GMP offline
[11C] PK11195 Translocator protein (TSPO) expression GMP
[11C] MDL 100,907 Serotonin 5-HT2A receptor GMP offline
[11C] DASB Serotonin transporter GMP offline
[11C] Antisense compound Apoptosis GMP offline
[11C] Leucine Protein synthesis GMP
[11C] Methionine Protein synthesis GMP
[11C] Verapamil P-glycoprotein transporter GMP offline
[11C] Diprenorphine Non-subtype selective opiate receptor GMP offline
[11C] Rosuvastatin Non-GMP
[11C] Temozolomide Chemotherapeutic Non-GMP
[18F] UCB-H Synaptic tracer Non-GMP
[18F] FLT Proliferation GMP offline
[18F] F-DOPA Dopamine synthesis GMP
[18F] GE-180 Translocator protein (TSPO) expression GMP
[18F] Flutemetamol Amyloid plaque GMP
[18F] FAZA Hypoxia GMP
[18F] FTHA Fatty acid metabolism Non-GMP
[18F] Labelling of peptides/proteins Various Non-GMP
[18F] DPA-713/714 Translocator protein (TSPO) expression Non-GMP
[18F] Interleukin-1RA Neuro-inflammation Non-GMP
[18F] Anti-b amyloid peptide Alzheimer’s disease Non-GMP
[18F] Cell matrix octapeptide Tissue engineering Non-GMP
[18F] FS03 Sodium-Iodide Symporter Non-GMP
[18F] glutamine Tumour metabolism Non-GMP
[18F] RGD peptide Angiogenesis Non-GMP
[18F] Her2 Nanobody Oncology Non-GMP
[18F] MMR Nanobody Inflammation Non-GMP
[18F] rinse NEMA testing Non-GMP
[18F] Sigma-1 Sigma 1 (σ1) receptor Non-GMP
[64Cu] Histidine Anhydrase II functions Non-GMP
[124I] mIBG Noradrenaline analogue GMP
[89Zr] Cetuximab Oncology Non-GMP
[89Zr] Bevacizumab Oncology Non-GMP
[89Zr] Labelled leukocytes Inflammation Non-GMP

We are seeking to extend our tracer programme and are happy to talk to interested parties about this. Please contact our Director of Radiochemistry, Dr Adam McMahon, for a discussion.

Contact

Mike Green
Production Team Leader
T: +44 (0) 161 275 0034
E: Michael.green@manchester.ac.uk