{"id":2688,"date":"2022-09-22T11:18:13","date_gmt":"2022-09-22T10:18:13","guid":{"rendered":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute-blog\/?page_id=2688"},"modified":"2025-06-25T15:54:29","modified_gmt":"2025-06-25T14:54:29","slug":"neuro-immunology","status":"publish","type":"page","link":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/research\/neuro-immunology\/","title":{"rendered":"Neuro-immunology"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; fullwidth=&#8221;on&#8221; next_background_color=&#8221;#000000&#8243; global_module=&#8221;322&#8243;][et_pb_fullwidth_menu global_parent=&#8221;322&#8243; _builder_version=&#8221;3.0.106&#8243; menu_id=&#8221;7&#8243; submenu_direction=&#8221;downwards&#8221; fullwidth_menu=&#8221;off&#8221; background_layout=&#8221;dark&#8221; module_class=&#8221;main-navigation&#8221; \/][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; fullwidth=&#8221;off&#8221; specialty=&#8221;off&#8221; transparent_background=&#8221;off&#8221; allow_player_pause=&#8221;off&#8221; inner_shadow=&#8221;off&#8221; parallax=&#8221;off&#8221; parallax_method=&#8221;on&#8221; make_fullwidth=&#8221;off&#8221; use_custom_width=&#8221;off&#8221; width_unit=&#8221;on&#8221; make_equal=&#8221;off&#8221; use_custom_gutter=&#8221;off&#8221; custom_padding=&#8221;0px||0px|&#8221; custom_css_main_element=&#8221;padding-top:0px&#8221; module_class=&#8221;header-image-section&#8221; prev_background_color=&#8221;#ffffff&#8221; next_background_color=&#8221;#ffffff&#8221;][et_pb_row allow_player_pause=&#8221;off&#8221; parallax=&#8221;off&#8221; parallax_method=&#8221;on&#8221; parallax_1=&#8221;off&#8221; parallax_method_1=&#8221;off&#8221; make_fullwidth=&#8221;off&#8221; use_custom_width=&#8221;off&#8221; width_unit=&#8221;on&#8221; use_custom_gutter=&#8221;off&#8221; make_equal=&#8221;off&#8221; custom_margin=&#8221;||0px|&#8221; custom_padding=&#8221;||0px|&#8221; module_class=&#8221;header-image&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;][et_pb_column type=&#8221;4_4&#8243;][et_pb_image src=&#8221;https:\/\/sites.manchester.ac.uk\/lydia-becker-institute-blog\/wp-content\/uploads\/sites\/69\/2022\/09\/neuro-immunology-banner.jpg&#8221; show_in_lightbox=&#8221;off&#8221; url_new_window=&#8221;off&#8221; use_overlay=&#8221;off&#8221; align=&#8221;left&#8221; always_center_on_mobile=&#8221;on&#8221; use_border_color=&#8221;off&#8221; force_fullwidth=&#8221;off&#8221; custom_margin=&#8221;0px|||&#8221; animation_direction=&#8221;left&#8221; show_bottom_space=&#8221;off&#8221; border_color_all=&#8221;#ffffff&#8221; _builder_version=&#8221;3.17.6&#8243; \/][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; fullwidth=&#8221;off&#8221; specialty=&#8221;off&#8221; transparent_background=&#8221;off&#8221; allow_player_pause=&#8221;off&#8221; inner_shadow=&#8221;off&#8221; parallax=&#8221;off&#8221; parallax_method=&#8221;on&#8221; make_fullwidth=&#8221;off&#8221; use_custom_width=&#8221;off&#8221; width_unit=&#8221;on&#8221; make_equal=&#8221;off&#8221; use_custom_gutter=&#8221;off&#8221; custom_padding=&#8221;||0px|&#8221; prev_background_color=&#8221;#ffffff&#8221; next_background_color=&#8221;#ffffff&#8221;][et_pb_row allow_player_pause=&#8221;off&#8221; parallax=&#8221;off&#8221; parallax_method=&#8221;on&#8221; parallax_1=&#8221;off&#8221; parallax_method_1=&#8221;off&#8221; make_fullwidth=&#8221;off&#8221; use_custom_width=&#8221;off&#8221; width_unit=&#8221;on&#8221; use_custom_gutter=&#8221;off&#8221; make_equal=&#8221;off&#8221; custom_margin=&#8221;||0px|&#8221; custom_padding=&#8221;||0px|&#8221; module_class=&#8221;breadcrumbs-row&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;][et_pb_column type=&#8221;4_4&#8243;][et_pb_text admin_label=&#8221;Breadcrumbs (do not remove)&#8221; background_layout=&#8221;light&#8221; text_orientation=&#8221;left&#8221; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; module_class=&#8221;breadcrumbs&#8221; custom_css_main_element=&#8221;border-bottom: 1px solid #ececed;&#8221; module_alignment=&#8221;left&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;]<\/p>\n<span><span><a href=\"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/\">Lydia Becker Institute of Immunology and Inflammation<\/a><\/span><\/span>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; fullwidth=&#8221;off&#8221; specialty=&#8221;on&#8221; transparent_background=&#8221;off&#8221; allow_player_pause=&#8221;off&#8221; inner_shadow=&#8221;off&#8221; parallax=&#8221;off&#8221; parallax_method=&#8221;on&#8221; parallax_1=&#8221;off&#8221; parallax_method_1=&#8221;off&#8221; parallax_2=&#8221;off&#8221; parallax_method_2=&#8221;off&#8221; make_fullwidth=&#8221;off&#8221; use_custom_width=&#8221;off&#8221; width_unit=&#8221;on&#8221; make_equal=&#8221;off&#8221; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; prev_background_color=&#8221;#ffffff&#8221; next_background_color=&#8221;#1d1d1d&#8221;][et_pb_column type=&#8221;1_3&#8243;][et_pb_sidebar admin_label=&#8221;Left Nav Sidebar&#8221; area=&#8221;et_pb_widget_area_1&#8243; orientation=&#8221;left&#8221; remove_border=&#8221;on&#8221; background_layout=&#8221;light&#8221; module_id=&#8221;left-nav-menu&#8221; show_border=&#8221;off&#8221; \/][\/et_pb_column][et_pb_column type=&#8221;2_3&#8243; specialty_columns=&#8221;2&#8243;][et_pb_row_inner admin_label=&#8221;Row&#8221;][et_pb_column_inner type=&#8221;4_4&#8243; saved_specialty_column_type=&#8221;2_3&#8243;][et_pb_text _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<h1>Neuro-immunology<\/h1>\n<p><iframe loading=\"lazy\" width=\"1080\" height=\"608\" src=\"https:\/\/www.youtube.com\/embed\/MUNbf-i1Rv4?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen title=\"Neuro-immunology Branch Introduction\"><\/iframe><\/p>\n<p class=\"subHeading\">The neuro-immunology branch of the Institute acts in partnership with the Geoffrey Jefferson Brain Research Centre to look at interactions between the brain, innervation of peripheral tissues and organs, and local immune responses which form the basis upon which patients experience symptoms in inflammatory diseases.<\/p>\n<p>This will enable us to:<\/p>\n<ul>\n<li>understand how these cellular mechanisms operate across different clinical conditions;<\/li>\n<li>explore the relevance of known neuroimmune mechanisms in new disease areas;<\/li>\n<li>identify novel neuroimmune mechanismswithin inflammatory diseases;<\/li>\n<li>guide the development of new treatments through translational pipelines, especially for stroke and brain tumours in partnership with the\u00a0<a href=\"https:\/\/gjbrainresearch.org\/\">Geoffrey Jefferson Brain Research Centre<\/a>.<\/li>\n<\/ul>\n<p>[\/et_pb_text][et_pb_button admin_label=&#8221;Button: Neuro-immunology case study&#8221; _builder_version=&#8221;3.17.6&#8243; button_text=&#8221;Neuro-immunology case study&#8221; button_url=&#8221;\/lydia-becker-institute\/research\/neuro-immunology\/neuro-immunology-case-study\/&#8221; \/][et_pb_text admin_label=&#8221;Spacing only&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p>\n&nbsp;<\/p>\n<p>[\/et_pb_text][et_pb_divider _builder_version=&#8221;3.17.6&#8243; \/][et_pb_text admin_label=&#8221;Text: People&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<h2>People<\/h2>\n<h3>Leads<\/h3>\n<p><a href=\"https:\/\/research.manchester.ac.uk\/en\/persons\/andrew.greenhalgh\">Dr Andrew Greenhalgh<\/a> (Lead)<\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/david.brough.html\">Professor David Brough<\/a> (Deputy lead)<\/p>\n<h3 style=\"padding-top: 1em;margin-bottom: -2em\">Principal investigators<\/h3>\n<p>[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][et_pb_row_inner admin_label=&#8221;Row&#8221;][et_pb_column_inner type=&#8221;1_2&#8243; saved_specialty_column_type=&#8221;2_3&#8243;][et_pb_text admin_label=&#8221;Text: PIs &#8211; LHS&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/en\/researchers\/stuart-allan(e0dd0cf7-cd2d-4ae1-a6aa-c3781e535276).html\">Professor Stuart Allan<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/brian.bigger.html\">Dr Brian Bigger<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/tracy.briggs.html\">Dr Tracy Briggs<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/hector.chinoy.html\">Dr Hector Chinoy<\/a><\/p>\n<p><a href=\"https:\/\/research.manchester.ac.uk\/en\/persons\/roy-chun-laam-ng\">Dr Roy Chun-Laam Ng<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/kevin.couper.html\">Dr Kevin Couper<\/a><\/p>\n<p><a href=\"https:\/\/research.manchester.ac.uk\/en\/persons\/giuseppe.dagostino\">Dr Giuseppe D&#8217;Agostino<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/daniel.davis.html\">Professor Daniel Davis<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/douglas.dyer.html\">Dr Douglas Dyer<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/sally.freeman.html\">Dr Sally Freeman<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/john.grainger-2.html\">Dr John Grainger<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/andrew.greenhalgh.html\">Dr Andrew Greenhalgh<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/christopher.griffiths.html\">Professor Christopher Griffiths<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/michael.harte.html\">Dr Mike Harte<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/matthew.hepworth.html\">Dr Matthew Hepworth<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/tracy.hussell.html\">Professor Tracy Hussell<\/a><\/p>\n<p><a href=\"https:\/\/research.manchester.ac.uk\/en\/persons\/reinmar.hager\">Dr Reinmar Hager<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/paul.kasher.html\">Dr Paul Kasher<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column_inner][et_pb_column_inner type=&#8221;1_2&#8243; saved_specialty_column_type=&#8221;2_3&#8243;][et_pb_text admin_label=&#8221;Text: PIs &#8211; RHS&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/en\/researchers\/christine-kleyn(4ca9ae3a-f0c3-4fb2-8687-694ffabcc931).html\">Dr Elise Kleyn<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/janine.lamb.html\">Dr Janine Lamb<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/catherine.lawrence.html\">Dr Catherine Lawrence<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/james.lilleker.html\">Dr James Lilleker<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/j.miyan.html\">Dr Jaleel Miyan<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/joanna.neill.html\">Professor Jo Neill<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/adrian.parry-jones.html\">Dr Adrian Parry-Jones<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/emmanuel.pinteaux.html\">Dr Emmanuel Pinteaux<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/ralf.paus.html\">Professor Ralf Paus<\/a><\/p>\n<p><a href=\"https:\/\/research.manchester.ac.uk\/en\/persons\/juan-quintana\">Dr Juan Quintana<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/federico.roncaroli.html\">Professor Federico Roncaroli<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/nancy.rothwell.html\">Professor Nancy Rothwell<\/a><\/p>\n<p><a href=\"https:\/\/research.manchester.ac.uk\/en\/persons\/matthew-sinton\">Dr Matthew Sinton<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/craig.smith-2.html\">Professor Craig Smith<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/jacky.smith.html\">Professor Jacky Smith<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/peter.talbot.html\">Dr Peter Talbot<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/Alexej.Verkhratsky.html\">Professor Alexei Verkhratsky<\/a><\/p>\n<p><a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/en\/researchers\/fong-kuan-wong(5b404aaa-3ebe-412f-b19b-e21b23803fe0).html\">Dr Fong Kuan Wong<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; 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background_layout=&#8221;dark&#8221; text_text_color=&#8221;#ffffff&#8221; parent_locked=&#8221;off&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;]<\/p>\n<h4>Contact Us<\/h4>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Contact Us&#8221; global_parent=&#8221;380&#8243; text_text_color=&#8221;#aaaaaa&#8221; parent_locked=&#8221;off&#8221; background_layout=&#8221;light&#8221; text_orientation=&#8221;left&#8221; use_border_color=&#8221;off&#8221; module_class=&#8221;contact-us&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p><a href=\"tel:+441613063771\">+44 (0)161 306 3771<\/a><\/p>\n<p>\u00a0<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243;][et_pb_text admin_label=&#8221;Find Us Title&#8221; global_parent=&#8221;380&#8243; background_layout=&#8221;dark&#8221; text_text_color=&#8221;#ffffff&#8221; parent_locked=&#8221;off&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<h4>Find Us<\/h4>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Address&#8221; global_parent=&#8221;380&#8243; background_layout=&#8221;dark&#8221; text_orientation=&#8221;left&#8221; use_border_color=&#8221;off&#8221; module_id=&#8221;address&#8221; parent_locked=&#8221;off&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p><a href=\"http:\/\/www.manchester.ac.uk\/discover\/maps\/interactive-map\/\">Lydia Becker Institute of Immunology and Inflammation<br \/><\/a><a href=\"http:\/\/www.manchester.ac.uk\/discover\/maps\/interactive-map\/\">Core Technology Facility\u00a0<br \/>46 Grafton Street<br \/>M13 9NT<\/a><\/p>\n<p>\u00a0<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243;][et_pb_text admin_label=&#8221;Connect Title&#8221; 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This will enable us to: understand how these [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":0,"parent":2510,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_exactmetrics_skip_tracking":false,"footnotes":""},"class_list":["post-2688","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/pages\/2688","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/comments?post=2688"}],"version-history":[{"count":18,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/pages\/2688\/revisions"}],"predecessor-version":[{"id":3990,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/pages\/2688\/revisions\/3990"}],"up":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/pages\/2510"}],"wp:attachment":[{"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/media?parent=2688"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}