{"id":2398,"date":"2022-03-02T16:37:07","date_gmt":"2022-03-02T16:37:07","guid":{"rendered":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute-blog\/?p=2398"},"modified":"2022-10-27T22:33:05","modified_gmt":"2022-10-27T21:33:05","slug":"covid-why-t-cell-vaccines-could-be-the-key-to-long-term-immunity","status":"publish","type":"post","link":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/2022\/03\/02\/covid-why-t-cell-vaccines-could-be-the-key-to-long-term-immunity\/","title":{"rendered":"COVID: why T cell vaccines could be the key to long-term immunity"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; fullwidth=&#8221;on&#8221; next_background_color=&#8221;#000000&#8243; global_module=&#8221;322&#8243;][et_pb_fullwidth_menu global_parent=&#8221;322&#8243; _builder_version=&#8221;3.0.106&#8243; menu_id=&#8221;7&#8243; submenu_direction=&#8221;downwards&#8221; fullwidth_menu=&#8221;off&#8221; background_layout=&#8221;dark&#8221; module_class=&#8221;main-navigation&#8221; \/][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; fullwidth=&#8221;off&#8221; specialty=&#8221;on&#8221; prev_background_color=&#8221;#000000&#8243;][et_pb_column type=&#8221;2_3&#8243; specialty_columns=&#8221;2&#8243;][et_pb_row_inner locked=&#8221;off&#8221;][et_pb_column_inner type=&#8221;4_4&#8243; saved_specialty_column_type=&#8221;2_3&#8243;][et_pb_post_title _builder_version=&#8221;3.0.106&#8243; title=&#8221;on&#8221; meta=&#8221;on&#8221; author=&#8221;on&#8221; date=&#8221;on&#8221; categories=&#8221;on&#8221; comments=&#8221;on&#8221; featured_image=&#8221;on&#8221; featured_placement=&#8221;above&#8221; text_color=&#8221;dark&#8221; text_background=&#8221;off&#8221; locked=&#8221;on&#8221; parent_locked=&#8221;off&#8221; \/][et_pb_text _builder_version=&#8221;3.17.6&#8243; background_layout=&#8221;light&#8221; parent_locked=&#8221;off&#8221;]<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-2378\" src=\"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute-blog\/wp-content\/uploads\/sites\/69\/2021\/12\/sheena-236x300.jpg\" alt=\"\" width=\"236\" height=\"300\" srcset=\"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2021\/12\/sheena-236x300.jpg 236w, https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2021\/12\/sheena-150x191.jpg 150w, https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2021\/12\/sheena-250x318.jpg 250w, https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2021\/12\/sheena.jpg 282w\" sizes=\"(max-width: 236px) 100vw, 236px\" \/><\/p>\n<p><strong>Prof Sheena Cruickshank<\/strong>\u00a0has written for <a href=\"https:\/\/theconversation.com\/covid-why-t-cell-vaccines-could-be-the-key-to-long-term-immunity-174494\">The Conversation<\/a> on the challenges posed by the Omicron variant of Covid-19 and how developing T-cell vaccines may be the key to unlocking long-term immunity from Covid:<\/p>\n<blockquote>\n<p>Many of the vaccines designed to date \u2013 including Moderna\u2019s, Pfizer\u2019s and AstraZeneca\u2019s \u2013 have focused on just one major target on the coronavirus: its spike protein. These vaccines have been tremendously effective at generating antibodies. They also stimulate a T cell response to the spike.<\/p>\n<p>&nbsp;<\/p>\n<p>But now that we understand more about the role of T cells, the importance of having a broad T cell response, and the issue of antibodies waning, perhaps we should consider refocusing our vaccine strategies on generating T cells and on targeting more than just one protein.<\/p>\n<\/blockquote>\n<p>You can read the full article <a href=\"https:\/\/theconversation.com\/covid-why-t-cell-vaccines-could-be-the-key-to-long-term-immunity-174494\">here<\/a><\/p>\n<p>[\/et_pb_text][et_pb_post_nav _builder_version=&#8221;3.0.106&#8243; in_same_term=&#8221;off&#8221; show_prev=&#8221;on&#8221; show_next=&#8221;on&#8221; prev_text=&#8221;Previous&#8221; next_text=&#8221;Next&#8221; locked=&#8221;on&#8221; parent_locked=&#8221;off&#8221; \/][et_pb_comments _builder_version=&#8221;3.0.106&#8243; show_avatar=&#8221;on&#8221; show_reply=&#8221;on&#8221; show_count=&#8221;on&#8221; background_layout=&#8221;light&#8221; header_font_size_tablet=&#8221;51&#8243; header_line_height_tablet=&#8221;2&#8243; custom_button=&#8221;on&#8221; button_icon_placement=&#8221;right&#8221; button_text_color=&#8221;#ffffff&#8221; button_use_icon=&#8221;off&#8221; locked=&#8221;on&#8221; parent_locked=&#8221;off&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_text_size__hover=&#8221;null&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover=&#8221;null&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover=&#8221;null&#8221; button_text_color__hover_enabled=&#8221;off&#8221; button_text_color__hover=&#8221;null&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_one_text_color__hover=&#8221;null&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover=&#8221;null&#8221; button_border_width__hover_enabled=&#8221;off&#8221; button_border_width__hover=&#8221;null&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_one_border_width__hover=&#8221;null&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover=&#8221;null&#8221; button_border_color__hover_enabled=&#8221;off&#8221; button_border_color__hover=&#8221;null&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; button_one_border_color__hover=&#8221;null&#8221; button_two_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover=&#8221;null&#8221; button_border_radius__hover_enabled=&#8221;off&#8221; button_border_radius__hover=&#8221;null&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover=&#8221;null&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover=&#8221;null&#8221; button_letter_spacing__hover_enabled=&#8221;off&#8221; button_letter_spacing__hover=&#8221;null&#8221; button_one_letter_spacing__hover_enabled=&#8221;off&#8221; button_one_letter_spacing__hover=&#8221;null&#8221; button_two_letter_spacing__hover_enabled=&#8221;off&#8221; button_two_letter_spacing__hover=&#8221;null&#8221; button_bg_color__hover_enabled=&#8221;off&#8221; button_bg_color__hover=&#8221;null&#8221; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_one_bg_color__hover=&#8221;null&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover=&#8221;null&#8221; \/][et_pb_text admin_label=&#8221;Related posts&#8221; _builder_version=&#8221;3.0.106&#8243; background_layout=&#8221;light&#8221; locked=&#8221;on&#8221; parent_locked=&#8221;off&#8221;]<\/p>\n<h1>Related<\/h1>\n<!-- relpost-thumb-wrapper --><div class=\"relpost-thumb-wrapper\"><!-- filter-class --><div class=\"relpost-thumb-container\"><h3>Related posts:<\/h3><div style=\"clear: both\"><\/div><div style=\"clear: both\"><\/div><!-- relpost-block-container --><div class=\"relpost-block-container relpost-block-column-layout\" style=\"--relposth-columns: 3;--relposth-columns_t: 2; --relposth-columns_m: 2\"><a href=\"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/2020\/03\/03\/significant-outbreak-likely\/\"class=\"relpost-block-single\" ><div class=\"relpost-custom-block-single\"><div class=\"relpost-block-single-image rpt-lazyload\" aria-label=\"Transmitting COVID-19 through surface contact.\" role=\"img\" data-bg=\"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2021\/01\/covid-transmission-150x150.jpg\" style=\"background: transparent no-repeat scroll 0% 0%; 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width: 150px; height: 150px; aspect-ratio: 1\/1;\"><\/div><div class=\"relpost-block-single-text\"  style=\"height: 75px;font-family: Arial;  font-size: 12px;  color: #333333;\"><h2 class=\"relpost_card_title\">These Are The Non-Negotiable Habits That Health Experts Practice Daily To Optimize Their Immunity.<\/h2><\/div><\/div><\/a><\/div><!-- close relpost-block-container --><div style=\"clear: both\"><\/div><\/div><!-- close filter class --><\/div><!-- close relpost-thumb-wrapper -->\n<p>[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243;][et_pb_sidebar _builder_version=&#8221;3.0.106&#8243; area=&#8221;sidebar-1&#8243; orientation=&#8221;left&#8221; show_border=&#8221;off&#8221; background_layout=&#8221;light&#8221; locked=&#8221;on&#8221; \/][\/et_pb_column][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prof Sheena Cruickshank\u00a0has written for The Conversation on the challenges posed by the Omicron variant of Covid-19 and how developing T-cell vaccines may be the key to unlocking long-term immunity from Covid: Many of the vaccines designed to date \u2013 including Moderna\u2019s, Pfizer\u2019s and AstraZeneca\u2019s \u2013 have focused on just one major target on the [&hellip;]<\/p>\n","protected":false},"author":5220,"featured_media":2405,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_exactmetrics_skip_tracking":false,"footnotes":""},"categories":[12,65,66,14],"tags":[],"class_list":["post-2398","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19","category-media-coverage","category-news","category-sheena-cruickshank"],"_links":{"self":[{"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/posts\/2398","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/users\/5220"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/comments?post=2398"}],"version-history":[{"count":7,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/posts\/2398\/revisions"}],"predecessor-version":[{"id":2407,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/posts\/2398\/revisions\/2407"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/media\/2405"}],"wp:attachment":[{"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/media?parent=2398"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/categories?post=2398"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/tags?post=2398"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}