{"id":3846,"date":"2024-09-27T09:24:23","date_gmt":"2024-09-27T08:24:23","guid":{"rendered":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/?p=3846"},"modified":"2024-09-27T09:30:11","modified_gmt":"2024-09-27T08:30:11","slug":"dr-jonathan-worboys-receives-fbmh-research-staff-of-the-year-2024-award","status":"publish","type":"post","link":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/2024\/09\/27\/dr-jonathan-worboys-receives-fbmh-research-staff-of-the-year-2024-award\/","title":{"rendered":"Dr Jonathan Worboys receives FBMH Research Staff of the Year 2024 Award"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; fullwidth=&#8221;on&#8221; next_background_color=&#8221;#000000&#8243; global_module=&#8221;322&#8243;][et_pb_fullwidth_menu global_parent=&#8221;322&#8243; _builder_version=&#8221;3.0.106&#8243; menu_id=&#8221;7&#8243; submenu_direction=&#8221;downwards&#8221; fullwidth_menu=&#8221;off&#8221; background_layout=&#8221;dark&#8221; module_class=&#8221;main-navigation&#8221; \/][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; fullwidth=&#8221;off&#8221; specialty=&#8221;on&#8221; prev_background_color=&#8221;#000000&#8243; next_background_color=&#8221;#1d1d1d&#8221;][et_pb_column type=&#8221;2_3&#8243; specialty_columns=&#8221;2&#8243;][et_pb_row_inner locked=&#8221;off&#8221;][et_pb_column_inner type=&#8221;4_4&#8243; saved_specialty_column_type=&#8221;2_3&#8243;][et_pb_post_title _builder_version=&#8221;3.0.106&#8243; title=&#8221;on&#8221; meta=&#8221;on&#8221; author=&#8221;on&#8221; date=&#8221;on&#8221; categories=&#8221;on&#8221; comments=&#8221;on&#8221; featured_image=&#8221;on&#8221; featured_placement=&#8221;above&#8221; text_color=&#8221;dark&#8221; text_background=&#8221;off&#8221; locked=&#8221;on&#8221; parent_locked=&#8221;off&#8221; \/][et_pb_text _builder_version=&#8221;3.17.6&#8243; background_layout=&#8221;light&#8221; parent_locked=&#8221;off&#8221;]<\/p>\n<p>Congratulations to <a href=\"https:\/\/research.manchester.ac.uk\/en\/persons\/jonathan.worboys\">Dr Jonathan Worboys<\/a> who received the &#8216;<strong>FBMH Research Staff of the Year Award 2024<\/strong>&#8216; at this year&#8217;s University of Manchester Research Staff Excellence <span class=\"markg9e9k42d0\">Award<\/span>s. Jonathan received the award for his ground-breaking research on how receptors on the surface of T cells arrange themselves to control their function.\u00a0<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-3847 \" src=\"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2024\/09\/GX0pCHAXEAAKEJx-793x1024.jpeg\" alt=\"Dr Jonathan Worboys FBMH Research Staff of the Year Award 2024\" width=\"530\" height=\"685\" srcset=\"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2024\/09\/GX0pCHAXEAAKEJx-793x1024.jpeg 793w, https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2024\/09\/GX0pCHAXEAAKEJx-232x300.jpeg 232w, https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2024\/09\/GX0pCHAXEAAKEJx-768x992.jpeg 768w, https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2024\/09\/GX0pCHAXEAAKEJx-150x194.jpeg 150w, https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2024\/09\/GX0pCHAXEAAKEJx-250x323.jpeg 250w, https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2024\/09\/GX0pCHAXEAAKEJx-350x452.jpeg 350w, https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2024\/09\/GX0pCHAXEAAKEJx-1080x1395.jpeg 1080w, https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2024\/09\/GX0pCHAXEAAKEJx-400x516.jpeg 400w, https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-content\/uploads\/sites\/69\/2024\/09\/GX0pCHAXEAAKEJx.jpeg 1586w\" sizes=\"(max-width: 530px) 100vw, 530px\" \/><\/p>\n<p>Commenting on Jonathan&#8217;s award Becker Executive Committee member\/DIIIRM Head of Division <a href=\"https:\/\/research.manchester.ac.uk\/en\/persons\/mark.travis\">Professor Mark Travis<\/a> said &#8220;I am delighted that Jonathan has been recognised with the FBMH Research Staff of the Year Award for 2024. Jonathan&#8217;s work leading up to this <span class=\"markg9e9k42d0\">award<\/span> showed that a specific receptor (called TIGIT) can rearrange itself into large clusters on the surface of T cells, leading to inhibition of T cell activity. This appears especially important within tumours, highlighting a new important therapeutic target to turn on the activity of T cells to kill cancer cells, and leading to a field-leading first-author publication in <a href=\"https:\/\/www.nature.com\/articles\/s41467-023-40755-3\"><i>Nature Communications<\/i>. <\/a><\/p>\n<p>Based on these findings, Jonathan has just been <span class=\"markg9e9k42d0\">award<\/span>ed a prestigious <a href=\"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/2024\/08\/01\/dr-jonathan-worboys-awarded-wellcome-career-development-award-fellowship\/\">Wellcome Trust Career Development <span class=\"markg9e9k42d0\">Award<\/span><\/a>, aiming to identify how other receptors clustering on T cells can inhibit their function, and how best to therapeutically target these pathways in cancer (worth almost \u00a31.5 million over 8 years).<\/p>\n<p>We are delighted that\u00a0Jonathan will be pursuing his independent research career in Manchester, and the Research Staff of the Year A<span class=\"markg9e9k42d0\">ward<\/span> is a perfect reward for his hard work as a post-doc leading up to this.&#8221;<\/p>\n<p>\u00a0<\/p>\n<p>[\/et_pb_text][et_pb_post_nav _builder_version=&#8221;3.0.106&#8243; 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at this year&#8217;s University of Manchester Research Staff Excellence Awards. Jonathan received the award for his ground-breaking research on how receptors on the surface of T cells arrange themselves to control their function.\u00a0Commenting on Jonathan&#8217;s award Becker Executive Committee [&hellip;]<\/p>\n","protected":false},"author":5220,"featured_media":3821,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_exactmetrics_skip_tracking":false,"footnotes":""},"categories":[66],"tags":[85,145],"class_list":["post-3846","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-awards","tag-jonathan-worboys"],"_links":{"self":[{"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/posts\/3846","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/users\/5220"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/comments?post=3846"}],"version-history":[{"count":3,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/posts\/3846\/revisions"}],"predecessor-version":[{"id":3850,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/posts\/3846\/revisions\/3850"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/media\/3821"}],"wp:attachment":[{"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/media?parent=3846"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/categories?post=3846"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/lydia-becker-institute\/wp-json\/wp\/v2\/tags?post=3846"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}