{"id":1656,"date":"2023-08-10T12:49:10","date_gmt":"2023-08-10T11:49:10","guid":{"rendered":"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/?page_id=1656"},"modified":"2023-09-05T14:53:55","modified_gmt":"2023-09-05T13:53:55","slug":"retinal-degeneration","status":"publish","type":"page","link":"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/key-areas-of-research\/retinal-degeneration\/","title":{"rendered":"Retinal degeneration"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; fullwidth=&#8221;on&#8221; next_background_color=&#8221;#000000&#8243; _builder_version=&#8221;3.17.6&#8243; global_module=&#8221;322&#8243;][et_pb_fullwidth_menu global_parent=&#8221;322&#8243; _builder_version=&#8221;3.0.106&#8243; menu_id=&#8221;7&#8243; submenu_direction=&#8221;downwards&#8221; fullwidth_menu=&#8221;off&#8221; background_layout=&#8221;dark&#8221; module_class=&#8221;main-navigation&#8221; \/][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; 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inner_shadow=&#8221;off&#8221; parallax=&#8221;off&#8221; parallax_method=&#8221;on&#8221; make_fullwidth=&#8221;off&#8221; use_custom_width=&#8221;off&#8221; width_unit=&#8221;on&#8221; make_equal=&#8221;off&#8221; use_custom_gutter=&#8221;off&#8221; custom_padding=&#8221;||0px|&#8221; prev_background_color=&#8221;#ffffff&#8221; next_background_color=&#8221;#ffffff&#8221;][et_pb_row allow_player_pause=&#8221;off&#8221; parallax=&#8221;off&#8221; parallax_method=&#8221;on&#8221; parallax_1=&#8221;off&#8221; parallax_method_1=&#8221;off&#8221; make_fullwidth=&#8221;off&#8221; use_custom_width=&#8221;off&#8221; width_unit=&#8221;on&#8221; use_custom_gutter=&#8221;off&#8221; make_equal=&#8221;off&#8221; custom_margin=&#8221;||0px|&#8221; custom_padding=&#8221;||0px|&#8221; module_class=&#8221;breadcrumbs-row&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;][et_pb_column type=&#8221;4_4&#8243;][et_pb_text admin_label=&#8221;Breadcrumbs (do not remove)&#8221; background_layout=&#8221;light&#8221; text_orientation=&#8221;left&#8221; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; module_class=&#8221;breadcrumbs&#8221; custom_css_main_element=&#8221;border-bottom: 1px solid #ececed;&#8221; module_alignment=&#8221;left&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;]<\/p>\n<span><span><a href=\"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/\">MVN2020<\/a><\/span><\/span>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; fullwidth=&#8221;off&#8221; specialty=&#8221;on&#8221; transparent_background=&#8221;off&#8221; allow_player_pause=&#8221;off&#8221; inner_shadow=&#8221;off&#8221; parallax=&#8221;off&#8221; parallax_method=&#8221;on&#8221; parallax_1=&#8221;off&#8221; parallax_method_1=&#8221;off&#8221; parallax_2=&#8221;off&#8221; parallax_method_2=&#8221;off&#8221; make_fullwidth=&#8221;off&#8221; use_custom_width=&#8221;off&#8221; width_unit=&#8221;on&#8221; make_equal=&#8221;off&#8221; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; prev_background_color=&#8221;#ffffff&#8221; next_background_color=&#8221;#ffffff&#8221;][et_pb_column type=&#8221;1_3&#8243;][et_pb_sidebar admin_label=&#8221;Left Nav Sidebar&#8221; area=&#8221;et_pb_widget_area_1&#8243; orientation=&#8221;left&#8221; remove_border=&#8221;on&#8221; background_layout=&#8221;light&#8221; module_id=&#8221;left-nav-menu&#8221; show_border=&#8221;off&#8221; \/][\/et_pb_column][et_pb_column type=&#8221;2_3&#8243; specialty_columns=&#8221;2&#8243;][et_pb_row_inner admin_label=&#8221;Row&#8221;][et_pb_column_inner type=&#8221;4_4&#8243; saved_specialty_column_type=&#8221;2_3&#8243;][et_pb_text admin_label=&#8221;Text: Retinal degeneration&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<h1 id=\"retinal-degeneration\">Retinal degeneration<\/h1>\n<p class=\"subHeading\">We pioneer new biological approaches to treat retinal degenerative conditions, including age-related macular degeneration and retinitis pigmentosa, which are the most common cause of blindness in the UK.<\/p>\n<p>Retinal degeneration is largely untreatable. We hope to develop new biological approaches to treat these conditions.<\/p>\n<p>We aim to better understand the clinical and biochemical consequences of retinal disease, and explain the genetic and environmental factors contributing to disease pathogenesis.<\/p>\n<p>With a strong translational focus, our goal is to bring these to the clinic and benefit patients with both novel treatments and advancements in existing clinical imaging and diagnostics.<\/p>\n<p>With access to world-leading facilities, Manchester is a leading institution for retinal disease research with key focus areas in:<\/p>\n<ul>\n<li>studying the genetics of retinal disorders;<\/li>\n<li>immune regulation and its underlying contribution to age-related macular degeneration;<\/li>\n<li>ocular angiogenesis and associated diseases such as diabetic retinopathy;<\/li>\n<li>clinical imaging, machine vision and the development of novel diagnostic tools;<\/li>\n<li>optogenetic approaches to restoring vision in retinal degeneration.<\/li>\n<\/ul>\n<p>[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; 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text_text_color=&#8221;#ffffff&#8221; parent_locked=&#8221;off&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;]<\/p>\n<h4>Contact Us<\/h4>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Contact Us&#8221; global_parent=&#8221;380&#8243; text_text_color=&#8221;#aaaaaa&#8221; parent_locked=&#8221;off&#8221; background_layout=&#8221;light&#8221; text_orientation=&#8221;left&#8221; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; module_class=&#8221;contact-us&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;]<\/p>\n<p>+44 (0) 161 306 6000<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243;][et_pb_text admin_label=&#8221;Find Us Title&#8221; global_parent=&#8221;380&#8243; background_layout=&#8221;dark&#8221; text_text_color=&#8221;#ffffff&#8221; parent_locked=&#8221;off&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;]<\/p>\n<h4>Find Us<\/h4>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Address&#8221; global_parent=&#8221;380&#8243; background_layout=&#8221;dark&#8221; text_orientation=&#8221;left&#8221; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; module_id=&#8221;address&#8221; parent_locked=&#8221;off&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;]<\/p>\n<p><a href=\"http:\/\/www.manchester.ac.uk\/discover\/maps\/interactive-map\/\">The University of Manchester<br \/>Oxford Rd<br \/>Manchester<br \/>M13 9PL<br \/>UK<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243;][et_pb_text admin_label=&#8221;Connect Title&#8221; global_parent=&#8221;380&#8243; background_layout=&#8221;dark&#8221; text_text_color=&#8221;#ffffff&#8221; parent_locked=&#8221;off&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_size=&#8221;initial&#8221;]<\/p>\n<h4>Connect With Us<\/h4>\n<p>[\/et_pb_text][et_pb_code admin_label=&#8221;Social Media&#8221; global_parent=&#8221;380&#8243; parent_locked=&#8221;off&#8221; _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<ul class=\"inlineList footer-socialIcons\"><!-- [et_pb_line_break_holder] --><\/p>\n<li><!-- [et_pb_line_break_holder] --> <a href=\"https:\/\/www.facebook.com\/TheUniversityOfManchester\"><!-- [et_pb_line_break_holder] --> <img loading=\"lazy\" decoding=\"async\" src=\"\/\/assets.manchester.ac.uk\/phase1\/templates\/images\/icon-facebook-50.png\" alt=\"Facebook page for The University of Manchester\" width=\"40\" height=\"40\" \/><!-- [et_pb_line_break_holder] --> <\/a><!-- [et_pb_line_break_holder] --><\/li>\n<p><!-- [et_pb_line_break_holder] --><\/p>\n<li><!-- [et_pb_line_break_holder] --> <a href=\"https:\/\/twitter.com\/OfficialUoM\"><!-- [et_pb_line_break_holder] --> <img loading=\"lazy\" decoding=\"async\" src=\"\/\/assets.manchester.ac.uk\/phase1\/templates\/images\/icon-twitter-50.png\" alt=\"Twitter page for The University of Manchester\" width=\"40\" height=\"40\" \/><!-- [et_pb_line_break_holder] --> <\/a><!-- [et_pb_line_break_holder] --><\/li>\n<p><!-- [et_pb_line_break_holder] --><\/p>\n<li><!-- [et_pb_line_break_holder] --> <a href=\"http:\/\/www.youtube.com\/universitymanchester\"><!-- [et_pb_line_break_holder] --> <img loading=\"lazy\" decoding=\"async\" src=\"\/\/assets.manchester.ac.uk\/phase1\/templates\/images\/icon-youtube-50.png\" alt=\"YouTube page for The University of Manchester\" width=\"40\" height=\"40\" \/><!-- [et_pb_line_break_holder] --> <\/a><!-- [et_pb_line_break_holder] --><\/li>\n<p><!-- [et_pb_line_break_holder] --><\/p>\n<li><!-- [et_pb_line_break_holder] --> <a href=\"https:\/\/instagram.com\/officialuom\/\"><!-- [et_pb_line_break_holder] --> <!-- [et_pb_line_break_holder] --> <img loading=\"lazy\" decoding=\"async\" src=\"\/\/assets.manchester.ac.uk\/phase1\/templates\/images\/icon-instagram-50.svg\" alt=\"Instagram page for The University of Manchester\" width=\"40\" height=\"40\" \/><!-- [et_pb_line_break_holder] --> <\/a><!-- [et_pb_line_break_holder] --><\/li>\n<p><!-- [et_pb_line_break_holder] --><\/ul>\n<p>[\/et_pb_code][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p><span><span><a href=\"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/\">MVN2020<\/a><\/span><\/span> Retinal degeneration We pioneer new biological approaches to treat retinal degenerative conditions, including age-related macular degeneration and retinitis pigmentosa, which are the most common cause of blindness in the UK. Retinal degeneration is largely untreatable. We hope to develop new biological approaches to treat these conditions. We aim to better understand the clinical and [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":0,"parent":1663,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_exactmetrics_skip_tracking":false,"footnotes":""},"class_list":["post-1656","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/wp-json\/wp\/v2\/pages\/1656","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/wp-json\/wp\/v2\/comments?post=1656"}],"version-history":[{"count":5,"href":"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/wp-json\/wp\/v2\/pages\/1656\/revisions"}],"predecessor-version":[{"id":1776,"href":"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/wp-json\/wp\/v2\/pages\/1656\/revisions\/1776"}],"up":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/wp-json\/wp\/v2\/pages\/1663"}],"wp:attachment":[{"href":"https:\/\/sites.manchester.ac.uk\/manchester-vision-network\/wp-json\/wp\/v2\/media?parent=1656"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}