[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section bb_built=”1″ use_custom_gutter=”on” gutter_width=”2″ specialty=”on” parallax_method_1=”off” parallax_method_2=”off” _builder_version=”3.0.74″ transparent_background=”off” prev_background_color=”#000000″ next_background_color=”#1d1d1d”][et_pb_column type=”1_3″][et_pb_sidebar admin_label=”Left Nav Sidebar” area=”et_pb_widget_area_1″ show_border=”off” module_id=”left-nav-menu” _builder_version=”3.0.74″ remove_border=”on”]<\/p>\n
<\/p>\n
[\/et_pb_sidebar][\/et_pb_column][et_pb_column type=”2_3″ specialty_columns=”2″][et_pb_row_inner admin_label=”Row” _builder_version=”3.0.47″][et_pb_column_inner type=”4_4″ saved_specialty_column_type=”2_3″][et_pb_text admin_label=”Text: Understanding normal and abnormal placental development and function” _builder_version=”3.17.6″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”left” use_border_color=”off”]<\/p>\n
Understanding normal and abnormal placental development and function<\/h1>\n
The placenta is the baby’s lifeline before birth. It must work optimally for the baby to grow properly and for the mother to remain healthy.<\/p>\n
One in 10 women experience pregnancy complications such as fetal growth restriction, pre-eclampsia and diabetes, which impair the growth and development of the baby, at worst leading to stillbirth.<\/p>\n
In all these complications, the baby fails to thrive because of abnormal development and function of the placenta. However, we still do not fully understand the origins of placental abnormalities. This lack of understanding impedes the development of treatments that will effectively restore placental function.<\/p>\n
We study hundreds of placentas in the laboratory every year to improve our understanding of how the placenta works in health and in disease.<\/p>\n
We focus on:<\/p>\n
- \n
- describing placental structure using a wide range of state-of-the-art imaging techniques such as 3D microscopy and MRI;<\/li>\n
- investigating how blood vessels that deliver blood to and from the placenta can influence blood flow;<\/li>\n
- understanding the regulation of important functions of the placenta, such as nutrient transport, production of energy and release of hormones needed for development of the placenta and baby;<\/li>\n
- investigating the impact of environmental exposures associated with adverse pregnancy outcome on placental function and fetal health;<\/li>\n
- developing mathematical models of placental structure, blood flow, and nutrient\/oxygen transfer to predict abnormal placental development function in disease and identify targets for therapy.<\/li>\n<\/ul>\n
<\/p>\n
[\/et_pb_text][et_pb_divider _builder_version=”3.17.6″]<\/p>\n
<\/p>\n
[\/et_pb_divider][et_pb_text admin_label=”Text: Contributing researchers” _builder_version=”3.17.6″]<\/p>\n
Contributing researchers<\/h2>\n
- \n
- John Aplin<\/a><\/li>\n
- Kylie Belchamber<\/a><\/li>\n
- Paul Brownbill<\/a><\/li>\n
- Igor Chernyavsky<\/a><\/li>\n
- Elizabeth Cottrell<\/a><\/li>\n
- Michelle Desforges<\/a><\/li>\n
- Mark Dilworth<\/a><\/li>\n
- Susan Greenwood<\/a><\/li>\n
- Lynda Harris<\/a><\/li>\n
- Alexander Heazell<\/a><\/li>\n
- Lucy Higgins<\/a><\/li>\n
- Colin Sibley<\/a><\/li>\n
- Adam Stevens<\/a><\/li>\n
- Melissa Westwood<\/a><\/li>\n<\/ul>\n
[\/et_pb_text][et_pb_divider _builder_version=”3.17.6″]<\/p>\n
<\/p>\n
[\/et_pb_divider][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][\/et_pb_section][et_pb_section bb_built=”1″ admin_label=”Connect Title” custom_padding=”0px||0px|” _builder_version=”3.0.90″ background_color=”#1d1d1d” module_class=”footer-section” prev_background_color=”#ffffff” global_module=”380″][et_pb_row admin_label=”row” global_parent=”380″ locked=”off” allow_player_pause=”off” parallax=”off” parallax_method=”on” parallax_1=”off” parallax_method_1=”off” parallax_2=”off” parallax_method_2=”off” parallax_3=”off” parallax_method_3=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” use_custom_gutter=”off” make_equal=”off” module_id=”footer-row” _builder_version=”3.0.89″][et_pb_column type=”1_3″][et_pb_text admin_label=”Contact Us Title” global_parent=”380″ background_layout=”dark” text_text_color=”#ffffff” parent_locked=”off” background_position=”top_left” background_repeat=”repeat” background_size=”initial”]<\/p>\n
Contact Us<\/h4>\n
[\/et_pb_text][et_pb_text admin_label=”Contact Us” global_parent=”380″ text_text_color=”#aaaaaa” parent_locked=”off” background_layout=”light” text_orientation=”left” use_border_color=”off” border_color=”#ffffff” border_style=”solid” module_class=”contact-us” background_position=”top_left” background_repeat=”repeat” background_size=”initial”]<\/p>\n
+44 (0) 161 306 6000<\/p>\n
[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″][et_pb_text admin_label=”Find Us Title” global_parent=”380″ background_layout=”dark” text_text_color=”#ffffff” parent_locked=”off” background_position=”top_left” background_repeat=”repeat” background_size=”initial”]<\/p>\n
Find Us<\/h4>\n
[\/et_pb_text][et_pb_text admin_label=”Address” global_parent=”380″ background_layout=”dark” text_orientation=”left” use_border_color=”off” border_color=”#ffffff” border_style=”solid” module_id=”address” parent_locked=”off” background_position=”top_left” background_repeat=”repeat” background_size=”initial”]<\/p>\n
- Kylie Belchamber<\/a><\/li>\n
- John Aplin<\/a><\/li>\n
![\"Facebook](\"\/\/assets.manchester.ac.uk\/phase1\/templates\/images\/icon-facebook-50.png\"){kind=icon}
<\/a><\/li>\n![\"Twitter](\"\/\/assets.manchester.ac.uk\/phase1\/templates\/images\/icon-twitter-50.png\"){kind=icon}
<\/a><\/li>\n![\"YouTube](\"\/\/assets.manchester.ac.uk\/phase1\/templates\/images\/icon-youtube-50.png\"){kind=icon}
<\/a><\/li>\n![\"Instagram](\"\/\/assets.manchester.ac.uk\/phase1\/templates\/images\/icon-instagram-50.svg\"){kind=icon}
<\/a><\/li>\n