{"id":1523,"date":"2021-01-19T11:59:28","date_gmt":"2021-01-19T11:59:28","guid":{"rendered":"https:\/\/sites.manchester.ac.uk\/mfig\/?p=1523"},"modified":"2024-02-14T13:23:13","modified_gmt":"2024-02-14T13:23:13","slug":"meet-the-phd-student-kayleigh-earle","status":"publish","type":"post","link":"https:\/\/sites.manchester.ac.uk\/mfig\/2021\/01\/19\/meet-the-phd-student-kayleigh-earle\/","title":{"rendered":"Meet the PhD student: Kayleigh Earle"},"content":{"rendered":"

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I am a first-year PhD student at Manchester Fungal Infection Group.<\/p>\n

My project, which is funded by the National Centre for the Replacement, Refinement & Reduction of Animals in Research (NC3Rs), is focused on developing an in vitro model to investigate Aspergillus fumigatus infections in people with cystic fibrosis.<\/p>\n

Within this project, I will be utilising CRISPR\/Cas9 mutagenesis to generate an isogenic cell line, which will be used to investigate the mechanisms of A. fumigatus persistence in CF patients.<\/p>\n

I will also be carrying out competitive fitness profiling of A. fumigatus using the model and a barcoded knockout library, which has been previously generated within the group.<\/p>\n

I completed my undergraduate degree in Microbiology at Queen\u2019s University of Belfast, before moving to Spain where I achieved my master\u2019s in Multidisciplinary Research in Experimental Sciences from Universitat Pompeu Fabra, together with the Barcelona Institute of Science and Technology.<\/p>\n

As part of this, I completed an eight-month internship at the Institute for Bioengineering of Catalonia in the Bacterial Infections: Antimicrobial Therapies group, which focused on developing an in vitro model to investigate chronic lung infections.<\/p>\n

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Related<\/h1>\n

Related posts:<\/h3>
<\/div>
<\/div>
<\/div>

Meet the PhD student: Harry Chown<\/h2><\/div><\/div><\/a>
<\/div>

New MFIG member: Welcome to S\u00e9bastien Ortiz<\/h2><\/div><\/div><\/a>
<\/div>

Meet the PhD student: Jamie Tindale<\/h2><\/div><\/div><\/a><\/div>
<\/div><\/div><\/div>\n

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Mrs Carolyn Glynn (Centre Manager)
Email:\u00a0carolyn.glynn@manchester.ac.uk<\/a>
Tel:\u00a0(+44) 0161 275 5482<\/a><\/p>\n

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