{"id":2052,"date":"2025-09-10T16:21:07","date_gmt":"2025-09-10T15:21:07","guid":{"rendered":"https:\/\/sites.manchester.ac.uk\/mfig\/?p=2052"},"modified":"2025-09-10T16:21:07","modified_gmt":"2025-09-10T15:21:07","slug":"dr-mike-bottery-awarded-a-wellcome-trust-career-development-award","status":"publish","type":"post","link":"https:\/\/sites.manchester.ac.uk\/mfig\/2025\/09\/10\/dr-mike-bottery-awarded-a-wellcome-trust-career-development-award\/","title":{"rendered":"Dr Mike Bottery awarded a Wellcome Trust Career Development Award"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; fullwidth=&#8221;on&#8221; next_background_color=&#8221;#000000&#8243; global_module=&#8221;322&#8243;][et_pb_fullwidth_menu global_parent=&#8221;322&#8243; _builder_version=&#8221;3.0.106&#8243; menu_id=&#8221;7&#8243; submenu_direction=&#8221;downwards&#8221; fullwidth_menu=&#8221;off&#8221; background_layout=&#8221;dark&#8221; module_class=&#8221;main-navigation&#8221; \/][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; _builder_version=&#8221;3.0.47&#8243; prev_background_color=&#8221;#000000&#8243; next_background_color=&#8221;#1d1d1d&#8221;][et_pb_column type=&#8221;2_3&#8243; specialty_columns=&#8221;2&#8243;][et_pb_row_inner _builder_version=&#8221;3.0.47&#8243; locked=&#8221;off&#8221;][et_pb_column_inner type=&#8221;4_4&#8243; saved_specialty_column_type=&#8221;2_3&#8243;][et_pb_post_title featured_placement=&#8221;above&#8221; _builder_version=&#8221;3.0.106&#8243; locked=&#8221;on&#8221;]<\/p>\n<p>[\/et_pb_post_title][et_pb_text _builder_version=&#8221;3.17.6&#8243;]<\/p>\n<p>I\u2019m excited to share that I\u2019ve been awarded a Wellcome Trust Career Development Award to address the remarkable evolutionary adaptability of the human fungal pathogen Aspergillus fumigatus.<\/p>\n<p>Serious fungal infections pose a unique challenge to human health, causing severe and life-threatening disease. Antifungal medications are essential for the treatment of fungal disease, but resistance is rapidly emerging across the globe. This is particularly\u00a0concerning for A. fumigatus, which is responsible for more deaths than any other fungal pathogen.\u00a0<span style=\"font-size: 16px\">Understanding the factors driving the remarkable adaptability of\u00a0A. fumigatus is essential for developing effective strategies to mitigate the risk of resistance\u00a0emergence. <\/span><\/p>\n<p><span style=\"font-size: 16px\">Through the fellowship, I will establish my lab group to investigate how mutation, horizontal gene transfer and sexual reproduction each contribute to the adaptability of A. fumigatus. By unravelling the complex interplay of genetic and environmental factors that shape A. fumigatus evolution, this research will provide critical information needed to combat the growing threat of drug-resistant fungal infections.<\/span><\/p>\n<p>Many thanks to the Wellcome Trust for giving me this opportunity to establish my lab; I am excited to continue my research journey in fungal evolution.<\/p>\n<p><em>\u00a0<\/em><\/p>\n<p>[\/et_pb_text][et_pb_post_nav in_same_term=&#8221;off&#8221; prev_text=&#8221;Previous&#8221; next_text=&#8221;Next&#8221; _builder_version=&#8221;3.0.106&#8243; locked=&#8221;on&#8221;]<\/p>\n<p>[\/et_pb_post_nav][et_pb_comments _builder_version=&#8221;3.16&#8243; header_font_size_tablet=&#8221;51&#8243; header_line_height_tablet=&#8221;2&#8243; custom_button=&#8221;on&#8221; button_text_color=&#8221;#ffffff&#8221; button_use_icon=&#8221;off&#8221; locked=&#8221;on&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_text_size__hover=&#8221;null&#8221; 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button_two_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover=&#8221;null&#8221; button_border_radius__hover_enabled=&#8221;off&#8221; button_border_radius__hover=&#8221;null&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover=&#8221;null&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover=&#8221;null&#8221; button_letter_spacing__hover_enabled=&#8221;off&#8221; button_letter_spacing__hover=&#8221;null&#8221; button_one_letter_spacing__hover_enabled=&#8221;off&#8221; button_one_letter_spacing__hover=&#8221;null&#8221; button_two_letter_spacing__hover_enabled=&#8221;off&#8221; button_two_letter_spacing__hover=&#8221;null&#8221; button_bg_color__hover_enabled=&#8221;off&#8221; button_bg_color__hover=&#8221;null&#8221; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_one_bg_color__hover=&#8221;null&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover=&#8221;null&#8221;]<\/p>\n<p>[\/et_pb_comments][et_pb_text admin_label=&#8221;Related posts&#8221; _builder_version=&#8221;3.0.106&#8243; locked=&#8221;on&#8221;]<\/p>\n<h1>Related<\/h1>\n<!-- relpost-thumb-wrapper --><div class=\"relpost-thumb-wrapper\"><!-- filter-class --><div class=\"relpost-thumb-container\"><h3>Related posts:<\/h3><div style=\"clear: both\"><\/div><div style=\"clear: both\"><\/div><!-- relpost-block-container --><div class=\"relpost-block-container relpost-block-column-layout\" style=\"--relposth-columns: 3;--relposth-columns_t: 2; --relposth-columns_m: 2\"><a href=\"https:\/\/sites.manchester.ac.uk\/mfig\/2025\/07\/04\/dr-margherita-bertuzzi-awarded-wellcome-trust-fungal-adaptation-grant-in-collaboration-with-dr-becky-hall-to-study-mucorales-adaptation\/\"class=\"relpost-block-single\" ><div class=\"relpost-custom-block-single\"><div class=\"relpost-block-single-image rpt-lazyload\" aria-hidden=\"true\" role=\"img\" data-bg=\"https:\/\/sites.manchester.ac.uk\/mfig\/wp-content\/uploads\/sites\/267\/2025\/07\/MBe-Group-150x150.jpg\" style=\"background: transparent no-repeat scroll 0% 0%; 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Serious fungal infections pose a unique challenge to human health, causing severe and life-threatening disease. Antifungal medications are essential for the treatment of fungal disease, but resistance is [&hellip;]<\/p>\n","protected":false},"author":6897,"featured_media":2057,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_exactmetrics_skip_tracking":false,"footnotes":""},"categories":[13],"tags":[],"class_list":["post-2052","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-good-news"],"_links":{"self":[{"href":"https:\/\/sites.manchester.ac.uk\/mfig\/wp-json\/wp\/v2\/posts\/2052","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.manchester.ac.uk\/mfig\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.manchester.ac.uk\/mfig\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/mfig\/wp-json\/wp\/v2\/users\/6897"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/mfig\/wp-json\/wp\/v2\/comments?post=2052"}],"version-history":[{"count":5,"href":"https:\/\/sites.manchester.ac.uk\/mfig\/wp-json\/wp\/v2\/posts\/2052\/revisions"}],"predecessor-version":[{"id":2092,"href":"https:\/\/sites.manchester.ac.uk\/mfig\/wp-json\/wp\/v2\/posts\/2052\/revisions\/2092"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/mfig\/wp-json\/wp\/v2\/media\/2057"}],"wp:attachment":[{"href":"https:\/\/sites.manchester.ac.uk\/mfig\/wp-json\/wp\/v2\/media?parent=2052"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/mfig\/wp-json\/wp\/v2\/categories?post=2052"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.manchester.ac.uk\/mfig\/wp-json\/wp\/v2\/tags?post=2052"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}