With my background in studying pathogen adaptation responses, I then focused on investigating how lung epithelium influences mucosal immune responses to pulmonary mycosis, further enhancing my core expertise in fungal pathogenesis and infection immunity.<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Congratulations to Dr Margherita Bertuzzi, who\u00a0has been awarded funding to provide a fully funded PhD studentship tackling fungal lung infections by the Humane Research Trust.<\/p>\n
Dr Margherita Bertuzzi in collaboration with\u00a0Dr Raveen Tank (University of Manchester), Prof Marc Thilo Figge (Friedrich Schiller University), Prof Terry Tetley (Imperial College London) and their PhD candidate Keira Gordon\u00a0will develop a microfluidic \u2018lung-on-a-chip\u2019 platform\u00a0within a fully humanised system. Whilst importantly, the model will use animal-free culture media and recombinant antibodies, ending reliance on animal-derived products. <\/span><\/p>\nTo find out more information on The Humane Research Trust and this project or other projects they are supporting you can visit their website here<\/a>.<\/span><\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Congratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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\nCongratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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\nCongratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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We are delighted to announce that Manchester University lecturer Dr Margherita Bertuzzi has been awarded a New Investigator Research Grant by the Medical Research Council (MRC) to study Aspergillus fumigatus<\/em>-epithelial interactions, how these influence immune responses and how they are dysregulated in disease.<\/p>\nAirborne spores of the most prominent fungal pathogen of human lungs, Aspergillus fumigatus<\/em>, are a major component of the air we breathe and are responsible for more than 3 million chronic infections and initiate over 200,000 invasive diseases annually worldwide. Some groups of severely immunocompromised patients, such as those undergoing bone marrow transplants, have just a 10% survival rate once a fungal infection is contracted.<\/p>\n\u201cRemarkably, while fungal diseases cause more deaths annually than tuberculosis or malaria, we still lack effective drugs to treat many of these infections,\u201d said Dr Bertuzzi, who is principal investigator of the three-year project. \u201cObtaining first-in-field insights into the mechanistic basis of the antifungal potency of the airway epithelium will open avenues for the development of novel immunomodulatory therapeutic strategies to facilitate treatment of lung diseases caused by Aspergillus fumigatus<\/em> and other respiratory pathogens.\u201d<\/p>\nThe New Investigator Research Grant is a competitive award aimed at researchers who are in the process of becoming independent Principal Investigators. The award will support Dr Bertuzzi\u2019s research which focuses on the epithelial interactions with inhaled respiratory pathogens and the role of these events in health and disease; how these interactions affect communication with other components of human immune and inflammatory cascades, and the technical know-how to translate this knowledge into human benefit.<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Prof Mike Bromley (Centre Director)<\/strong>
Email: mike.bromley@manchester.ac.uk<\/a><\/p>\nDr Margherita Bertuzzi
<\/strong>Email:\u00a0margherita.bertuzzi@manchester.ac.uk<\/a>\u00a0<\/p>\n\u00a0<\/p>\n
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Related posts:<\/h3><\/div><\/div><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Congratulations to Dr Margherita Bertuzzi, who\u00a0has been awarded funding to provide a fully funded PhD studentship tackling fungal lung infections by the Humane Research Trust.<\/p>\n
Dr Margherita Bertuzzi in collaboration with\u00a0Dr Raveen Tank (University of Manchester), Prof Marc Thilo Figge (Friedrich Schiller University), Prof Terry Tetley (Imperial College London) and their PhD candidate Keira Gordon\u00a0will develop a microfluidic \u2018lung-on-a-chip\u2019 platform\u00a0within a fully humanised system. Whilst importantly, the model will use animal-free culture media and recombinant antibodies, ending reliance on animal-derived products. <\/span><\/p>\nTo find out more information on The Humane Research Trust and this project or other projects they are supporting you can visit their website here<\/a>.<\/span><\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Congratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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\nCongratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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\nCongratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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We are delighted to announce that Manchester University lecturer Dr Margherita Bertuzzi has been awarded a New Investigator Research Grant by the Medical Research Council (MRC) to study Aspergillus fumigatus<\/em>-epithelial interactions, how these influence immune responses and how they are dysregulated in disease.<\/p>\nAirborne spores of the most prominent fungal pathogen of human lungs, Aspergillus fumigatus<\/em>, are a major component of the air we breathe and are responsible for more than 3 million chronic infections and initiate over 200,000 invasive diseases annually worldwide. Some groups of severely immunocompromised patients, such as those undergoing bone marrow transplants, have just a 10% survival rate once a fungal infection is contracted.<\/p>\n\u201cRemarkably, while fungal diseases cause more deaths annually than tuberculosis or malaria, we still lack effective drugs to treat many of these infections,\u201d said Dr Bertuzzi, who is principal investigator of the three-year project. \u201cObtaining first-in-field insights into the mechanistic basis of the antifungal potency of the airway epithelium will open avenues for the development of novel immunomodulatory therapeutic strategies to facilitate treatment of lung diseases caused by Aspergillus fumigatus<\/em> and other respiratory pathogens.\u201d<\/p>\nThe New Investigator Research Grant is a competitive award aimed at researchers who are in the process of becoming independent Principal Investigators. The award will support Dr Bertuzzi\u2019s research which focuses on the epithelial interactions with inhaled respiratory pathogens and the role of these events in health and disease; how these interactions affect communication with other components of human immune and inflammatory cascades, and the technical know-how to translate this knowledge into human benefit.<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Prof Mike Bromley (Centre Director)<\/strong>
Email: mike.bromley@manchester.ac.uk<\/a><\/p>\nDr Margherita Bertuzzi
<\/strong>Email:\u00a0margherita.bertuzzi@manchester.ac.uk<\/a>\u00a0<\/p>\n\u00a0<\/p>\n
\u00a0<\/p>\n
\u00a0<\/p>\n
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Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Congratulations to Dr Margherita Bertuzzi, who\u00a0has been awarded funding to provide a fully funded PhD studentship tackling fungal lung infections by the Humane Research Trust.<\/p>\n
Dr Margherita Bertuzzi in collaboration with\u00a0Dr Raveen Tank (University of Manchester), Prof Marc Thilo Figge (Friedrich Schiller University), Prof Terry Tetley (Imperial College London) and their PhD candidate Keira Gordon\u00a0will develop a microfluidic \u2018lung-on-a-chip\u2019 platform\u00a0within a fully humanised system. Whilst importantly, the model will use animal-free culture media and recombinant antibodies, ending reliance on animal-derived products. <\/span><\/p>\nTo find out more information on The Humane Research Trust and this project or other projects they are supporting you can visit their website here<\/a>.<\/span><\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Congratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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\nCongratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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\nCongratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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We are delighted to announce that Manchester University lecturer Dr Margherita Bertuzzi has been awarded a New Investigator Research Grant by the Medical Research Council (MRC) to study Aspergillus fumigatus<\/em>-epithelial interactions, how these influence immune responses and how they are dysregulated in disease.<\/p>\nAirborne spores of the most prominent fungal pathogen of human lungs, Aspergillus fumigatus<\/em>, are a major component of the air we breathe and are responsible for more than 3 million chronic infections and initiate over 200,000 invasive diseases annually worldwide. Some groups of severely immunocompromised patients, such as those undergoing bone marrow transplants, have just a 10% survival rate once a fungal infection is contracted.<\/p>\n\u201cRemarkably, while fungal diseases cause more deaths annually than tuberculosis or malaria, we still lack effective drugs to treat many of these infections,\u201d said Dr Bertuzzi, who is principal investigator of the three-year project. \u201cObtaining first-in-field insights into the mechanistic basis of the antifungal potency of the airway epithelium will open avenues for the development of novel immunomodulatory therapeutic strategies to facilitate treatment of lung diseases caused by Aspergillus fumigatus<\/em> and other respiratory pathogens.\u201d<\/p>\nThe New Investigator Research Grant is a competitive award aimed at researchers who are in the process of becoming independent Principal Investigators. The award will support Dr Bertuzzi\u2019s research which focuses on the epithelial interactions with inhaled respiratory pathogens and the role of these events in health and disease; how these interactions affect communication with other components of human immune and inflammatory cascades, and the technical know-how to translate this knowledge into human benefit.<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Prof Mike Bromley (Centre Director)<\/strong>
Email: mike.bromley@manchester.ac.uk<\/a><\/p>\nDr Margherita Bertuzzi
<\/strong>Email:\u00a0margherita.bertuzzi@manchester.ac.uk<\/a>\u00a0<\/p>\n\u00a0<\/p>\n
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Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Congratulations to Dr Margherita Bertuzzi, who\u00a0has been awarded funding to provide a fully funded PhD studentship tackling fungal lung infections by the Humane Research Trust.<\/p>\n
Dr Margherita Bertuzzi in collaboration with\u00a0Dr Raveen Tank (University of Manchester), Prof Marc Thilo Figge (Friedrich Schiller University), Prof Terry Tetley (Imperial College London) and their PhD candidate Keira Gordon\u00a0will develop a microfluidic \u2018lung-on-a-chip\u2019 platform\u00a0within a fully humanised system. Whilst importantly, the model will use animal-free culture media and recombinant antibodies, ending reliance on animal-derived products. <\/span><\/p>\nTo find out more information on The Humane Research Trust and this project or other projects they are supporting you can visit their website here<\/a>.<\/span><\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Congratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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\nCongratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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\nCongratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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We are delighted to announce that Manchester University lecturer Dr Margherita Bertuzzi has been awarded a New Investigator Research Grant by the Medical Research Council (MRC) to study Aspergillus fumigatus<\/em>-epithelial interactions, how these influence immune responses and how they are dysregulated in disease.<\/p>\nAirborne spores of the most prominent fungal pathogen of human lungs, Aspergillus fumigatus<\/em>, are a major component of the air we breathe and are responsible for more than 3 million chronic infections and initiate over 200,000 invasive diseases annually worldwide. Some groups of severely immunocompromised patients, such as those undergoing bone marrow transplants, have just a 10% survival rate once a fungal infection is contracted.<\/p>\n\u201cRemarkably, while fungal diseases cause more deaths annually than tuberculosis or malaria, we still lack effective drugs to treat many of these infections,\u201d said Dr Bertuzzi, who is principal investigator of the three-year project. \u201cObtaining first-in-field insights into the mechanistic basis of the antifungal potency of the airway epithelium will open avenues for the development of novel immunomodulatory therapeutic strategies to facilitate treatment of lung diseases caused by Aspergillus fumigatus<\/em> and other respiratory pathogens.\u201d<\/p>\nThe New Investigator Research Grant is a competitive award aimed at researchers who are in the process of becoming independent Principal Investigators. The award will support Dr Bertuzzi\u2019s research which focuses on the epithelial interactions with inhaled respiratory pathogens and the role of these events in health and disease; how these interactions affect communication with other components of human immune and inflammatory cascades, and the technical know-how to translate this knowledge into human benefit.<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Prof Mike Bromley (Centre Director)<\/strong>
Email: mike.bromley@manchester.ac.uk<\/a><\/p>\nDr Margherita Bertuzzi
<\/strong>Email:\u00a0margherita.bertuzzi@manchester.ac.uk<\/a>\u00a0<\/p>\n\u00a0<\/p>\n
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Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Congratulations to Dr Margherita Bertuzzi, who\u00a0has been awarded funding to provide a fully funded PhD studentship tackling fungal lung infections by the Humane Research Trust.<\/p>\n
Dr Margherita Bertuzzi in collaboration with\u00a0Dr Raveen Tank (University of Manchester), Prof Marc Thilo Figge (Friedrich Schiller University), Prof Terry Tetley (Imperial College London) and their PhD candidate Keira Gordon\u00a0will develop a microfluidic \u2018lung-on-a-chip\u2019 platform\u00a0within a fully humanised system. Whilst importantly, the model will use animal-free culture media and recombinant antibodies, ending reliance on animal-derived products. <\/span><\/p>\nTo find out more information on The Humane Research Trust and this project or other projects they are supporting you can visit their website here<\/a>.<\/span><\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Congratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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Related<\/h1>\nRelated posts:<\/h3><\/div><\/div><\/div>Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>Meet the team: Helen Harris<\/h2><\/div><\/div><\/a><\/div>Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div><\/div><\/div><\/div>\n[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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\nCongratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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\nCongratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n[\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n
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We are delighted to announce that Manchester University lecturer Dr Margherita Bertuzzi has been awarded a New Investigator Research Grant by the Medical Research Council (MRC) to study Aspergillus fumigatus<\/em>-epithelial interactions, how these influence immune responses and how they are dysregulated in disease.<\/p>\nAirborne spores of the most prominent fungal pathogen of human lungs, Aspergillus fumigatus<\/em>, are a major component of the air we breathe and are responsible for more than 3 million chronic infections and initiate over 200,000 invasive diseases annually worldwide. Some groups of severely immunocompromised patients, such as those undergoing bone marrow transplants, have just a 10% survival rate once a fungal infection is contracted.<\/p>\n\u201cRemarkably, while fungal diseases cause more deaths annually than tuberculosis or malaria, we still lack effective drugs to treat many of these infections,\u201d said Dr Bertuzzi, who is principal investigator of the three-year project. \u201cObtaining first-in-field insights into the mechanistic basis of the antifungal potency of the airway epithelium will open avenues for the development of novel immunomodulatory therapeutic strategies to facilitate treatment of lung diseases caused by Aspergillus fumigatus<\/em> and other respiratory pathogens.\u201d<\/p>\nThe New Investigator Research Grant is a competitive award aimed at researchers who are in the process of becoming independent Principal Investigators. The award will support Dr Bertuzzi\u2019s research which focuses on the epithelial interactions with inhaled respiratory pathogens and the role of these events in health and disease; how these interactions affect communication with other components of human immune and inflammatory cascades, and the technical know-how to translate this knowledge into human benefit.<\/p>\n
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Prof Mike Bromley (Centre Director)<\/strong>
Email: mike.bromley@manchester.ac.uk<\/a><\/p>\nDr Margherita Bertuzzi
<\/strong>Email:\u00a0margherita.bertuzzi@manchester.ac.uk<\/a>\u00a0<\/p>\n\u00a0<\/p>\n
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Congratulations to Dr Margherita Bertuzzi, who\u00a0has been awarded funding to provide a fully funded PhD studentship tackling fungal lung infections by the Humane Research Trust.<\/p>\n
Dr Margherita Bertuzzi in collaboration with\u00a0Dr Raveen Tank (University of Manchester), Prof Marc Thilo Figge (Friedrich Schiller University), Prof Terry Tetley (Imperial College London) and their PhD candidate Keira Gordon\u00a0will develop a microfluidic \u2018lung-on-a-chip\u2019 platform\u00a0within a fully humanised system. Whilst importantly, the model will use animal-free culture media and recombinant antibodies, ending reliance on animal-derived products. <\/span><\/p>\n To find out more information on The Humane Research Trust and this project or other projects they are supporting you can visit their website here<\/a>.<\/span><\/p>\n [\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_post_nav][et_pb_comments _builder_version=”3.16″ header_font_size_tablet=”51″ header_line_height_tablet=”2″ custom_button=”on” button_text_color=”#ffffff” button_use_icon=”off” locked=”on” button_text_size__hover_enabled=”off” button_text_size__hover=”null” button_one_text_size__hover_enabled=”off” button_one_text_size__hover=”null” button_two_text_size__hover_enabled=”off” button_two_text_size__hover=”null” button_text_color__hover_enabled=”off” button_text_color__hover=”null” button_one_text_color__hover_enabled=”off” button_one_text_color__hover=”null” button_two_text_color__hover_enabled=”off” button_two_text_color__hover=”null” button_border_width__hover_enabled=”off” button_border_width__hover=”null” button_one_border_width__hover_enabled=”off” button_one_border_width__hover=”null” button_two_border_width__hover_enabled=”off” button_two_border_width__hover=”null” button_border_color__hover_enabled=”off” button_border_color__hover=”null” button_one_border_color__hover_enabled=”off” button_one_border_color__hover=”null” button_two_border_color__hover_enabled=”off” button_two_border_color__hover=”null” button_border_radius__hover_enabled=”off” button_border_radius__hover=”null” button_one_border_radius__hover_enabled=”off” button_one_border_radius__hover=”null” button_two_border_radius__hover_enabled=”off” button_two_border_radius__hover=”null” button_letter_spacing__hover_enabled=”off” button_letter_spacing__hover=”null” button_one_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover=”null” button_two_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover=”null” button_bg_color__hover_enabled=”off” button_bg_color__hover=”null” button_one_bg_color__hover_enabled=”off” button_one_bg_color__hover=”null” button_two_bg_color__hover_enabled=”off” button_two_bg_color__hover=”null”]<\/p>\n [\/et_pb_comments][et_pb_text admin_label=”Related posts” _builder_version=”3.0.106″ locked=”off”]<\/p>\n [\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_sidebar][\/et_pb_column][\/et_pb_section][et_pb_section bb_built=”1″ specialty=”on” _builder_version=”3.0.47″ prev_background_color=”#000000″ next_background_color=”#000000″][et_pb_column type=”2_3″ specialty_columns=”2″][et_pb_row_inner _builder_version=”3.0.47″ locked=”off”][et_pb_column_inner type=”4_4″ saved_specialty_column_type=”2_3″][et_pb_post_title featured_placement=”above” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_post_title][et_pb_text _builder_version=”3.17.6″]<\/p>\n Congratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n [\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_post_nav][et_pb_comments _builder_version=”3.16″ header_font_size_tablet=”51″ header_line_height_tablet=”2″ custom_button=”on” button_text_color=”#ffffff” button_use_icon=”off” locked=”on” button_text_size__hover_enabled=”off” button_text_size__hover=”null” button_one_text_size__hover_enabled=”off” button_one_text_size__hover=”null” button_two_text_size__hover_enabled=”off” button_two_text_size__hover=”null” button_text_color__hover_enabled=”off” button_text_color__hover=”null” button_one_text_color__hover_enabled=”off” button_one_text_color__hover=”null” button_two_text_color__hover_enabled=”off” button_two_text_color__hover=”null” button_border_width__hover_enabled=”off” button_border_width__hover=”null” button_one_border_width__hover_enabled=”off” button_one_border_width__hover=”null” button_two_border_width__hover_enabled=”off” button_two_border_width__hover=”null” button_border_color__hover_enabled=”off” button_border_color__hover=”null” button_one_border_color__hover_enabled=”off” button_one_border_color__hover=”null” button_two_border_color__hover_enabled=”off” button_two_border_color__hover=”null” button_border_radius__hover_enabled=”off” button_border_radius__hover=”null” button_one_border_radius__hover_enabled=”off” button_one_border_radius__hover=”null” button_two_border_radius__hover_enabled=”off” button_two_border_radius__hover=”null” button_letter_spacing__hover_enabled=”off” button_letter_spacing__hover=”null” button_one_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover=”null” button_two_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover=”null” button_bg_color__hover_enabled=”off” button_bg_color__hover=”null” button_one_bg_color__hover_enabled=”off” button_one_bg_color__hover=”null” button_two_bg_color__hover_enabled=”off” button_two_bg_color__hover=”null”]<\/p>\n [\/et_pb_comments][et_pb_text admin_label=”Related posts” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_sidebar][\/et_pb_column][\/et_pb_section][et_pb_section bb_built=”1″ specialty=”on” _builder_version=”3.0.47″ prev_background_color=”#000000″ next_background_color=”#000000″][et_pb_column type=”2_3″ specialty_columns=”2″][et_pb_row_inner _builder_version=”3.0.47″ locked=”off”][et_pb_column_inner type=”4_4″ saved_specialty_column_type=”2_3″][et_pb_post_title featured_placement=”above” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_post_title][et_pb_text _builder_version=”3.17.6″]<\/p>\n \nCongratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n [\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_post_nav][et_pb_comments _builder_version=”3.16″ header_font_size_tablet=”51″ header_line_height_tablet=”2″ custom_button=”on” button_text_color=”#ffffff” button_use_icon=”off” locked=”on” button_text_size__hover_enabled=”off” button_text_size__hover=”null” button_one_text_size__hover_enabled=”off” button_one_text_size__hover=”null” button_two_text_size__hover_enabled=”off” button_two_text_size__hover=”null” button_text_color__hover_enabled=”off” button_text_color__hover=”null” button_one_text_color__hover_enabled=”off” button_one_text_color__hover=”null” button_two_text_color__hover_enabled=”off” button_two_text_color__hover=”null” button_border_width__hover_enabled=”off” button_border_width__hover=”null” button_one_border_width__hover_enabled=”off” button_one_border_width__hover=”null” button_two_border_width__hover_enabled=”off” button_two_border_width__hover=”null” button_border_color__hover_enabled=”off” button_border_color__hover=”null” button_one_border_color__hover_enabled=”off” button_one_border_color__hover=”null” button_two_border_color__hover_enabled=”off” button_two_border_color__hover=”null” button_border_radius__hover_enabled=”off” button_border_radius__hover=”null” button_one_border_radius__hover_enabled=”off” button_one_border_radius__hover=”null” button_two_border_radius__hover_enabled=”off” button_two_border_radius__hover=”null” button_letter_spacing__hover_enabled=”off” button_letter_spacing__hover=”null” button_one_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover=”null” button_two_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover=”null” button_bg_color__hover_enabled=”off” button_bg_color__hover=”null” button_one_bg_color__hover_enabled=”off” button_one_bg_color__hover=”null” button_two_bg_color__hover_enabled=”off” button_two_bg_color__hover=”null”]<\/p>\n [\/et_pb_comments][et_pb_text admin_label=”Related posts” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_sidebar][\/et_pb_column][\/et_pb_section][et_pb_section bb_built=”1″ specialty=”on” _builder_version=”3.0.47″ prev_background_color=”#000000″ next_background_color=”#000000″][et_pb_column type=”2_3″ specialty_columns=”2″][et_pb_row_inner _builder_version=”3.0.47″ locked=”off”][et_pb_column_inner type=”4_4″ saved_specialty_column_type=”2_3″][et_pb_post_title featured_placement=”above” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_post_title][et_pb_text _builder_version=”3.17.6″]<\/p>\n \nCongratulations to Dr Can Zhao, Co-Founder of\u00a0UoM-MFIG spin-out InPepCide, who\u00a0has been awarded a place on the full Accelerator Programme, which offers start-up and scale-up support to early stage and growing life science businesses on their journey to success. More information can be found here<\/a>.<\/p>\n [\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_post_nav][et_pb_comments _builder_version=”3.16″ header_font_size_tablet=”51″ header_line_height_tablet=”2″ custom_button=”on” button_text_color=”#ffffff” button_use_icon=”off” locked=”on” button_text_size__hover_enabled=”off” button_text_size__hover=”null” button_one_text_size__hover_enabled=”off” button_one_text_size__hover=”null” button_two_text_size__hover_enabled=”off” button_two_text_size__hover=”null” button_text_color__hover_enabled=”off” button_text_color__hover=”null” button_one_text_color__hover_enabled=”off” button_one_text_color__hover=”null” button_two_text_color__hover_enabled=”off” button_two_text_color__hover=”null” button_border_width__hover_enabled=”off” button_border_width__hover=”null” button_one_border_width__hover_enabled=”off” button_one_border_width__hover=”null” button_two_border_width__hover_enabled=”off” button_two_border_width__hover=”null” button_border_color__hover_enabled=”off” button_border_color__hover=”null” button_one_border_color__hover_enabled=”off” button_one_border_color__hover=”null” button_two_border_color__hover_enabled=”off” button_two_border_color__hover=”null” button_border_radius__hover_enabled=”off” button_border_radius__hover=”null” button_one_border_radius__hover_enabled=”off” button_one_border_radius__hover=”null” button_two_border_radius__hover_enabled=”off” button_two_border_radius__hover=”null” button_letter_spacing__hover_enabled=”off” button_letter_spacing__hover=”null” button_one_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover=”null” button_two_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover=”null” button_bg_color__hover_enabled=”off” button_bg_color__hover=”null” button_one_bg_color__hover_enabled=”off” button_one_bg_color__hover=”null” button_two_bg_color__hover_enabled=”off” button_two_bg_color__hover=”null”]<\/p>\n [\/et_pb_comments][et_pb_text admin_label=”Related posts” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_sidebar][\/et_pb_column][\/et_pb_section][et_pb_section bb_built=”1″ admin_label=”section” fullwidth=”on” next_background_color=”#000000″ prev_background_color=”#000000″ global_module=”322″][et_pb_fullwidth_menu global_parent=”322″ _builder_version=”3.0.106″ menu_id=”7″ submenu_direction=”downwards” fullwidth_menu=”off” background_layout=”dark” module_class=”main-navigation” \/][\/et_pb_section][et_pb_section bb_built=”1″ specialty=”on” _builder_version=”3.0.47″ prev_background_color=”#000000″ next_background_color=”#1d1d1d”][et_pb_column type=”2_3″ specialty_columns=”2″][et_pb_row_inner _builder_version=”3.0.47″ locked=”off”][et_pb_column_inner type=”4_4″ saved_specialty_column_type=”2_3″][et_pb_post_title featured_placement=”above” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_post_title][et_pb_text _builder_version=”3.17.6″]<\/p>\n We are delighted to announce that Manchester University lecturer Dr Margherita Bertuzzi has been awarded a New Investigator Research Grant by the Medical Research Council (MRC) to study Aspergillus fumigatus<\/em>-epithelial interactions, how these influence immune responses and how they are dysregulated in disease.<\/p>\n Airborne spores of the most prominent fungal pathogen of human lungs, Aspergillus fumigatus<\/em>, are a major component of the air we breathe and are responsible for more than 3 million chronic infections and initiate over 200,000 invasive diseases annually worldwide. Some groups of severely immunocompromised patients, such as those undergoing bone marrow transplants, have just a 10% survival rate once a fungal infection is contracted.<\/p>\n \u201cRemarkably, while fungal diseases cause more deaths annually than tuberculosis or malaria, we still lack effective drugs to treat many of these infections,\u201d said Dr Bertuzzi, who is principal investigator of the three-year project. \u201cObtaining first-in-field insights into the mechanistic basis of the antifungal potency of the airway epithelium will open avenues for the development of novel immunomodulatory therapeutic strategies to facilitate treatment of lung diseases caused by Aspergillus fumigatus<\/em> and other respiratory pathogens.\u201d<\/p>\n The New Investigator Research Grant is a competitive award aimed at researchers who are in the process of becoming independent Principal Investigators. The award will support Dr Bertuzzi\u2019s research which focuses on the epithelial interactions with inhaled respiratory pathogens and the role of these events in health and disease; how these interactions affect communication with other components of human immune and inflammatory cascades, and the technical know-how to translate this knowledge into human benefit.<\/p>\n [\/et_pb_text][et_pb_post_nav in_same_term=”off” prev_text=”Previous” next_text=”Next” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_post_nav][et_pb_comments _builder_version=”3.16″ header_font_size_tablet=”51″ header_line_height_tablet=”2″ custom_button=”on” button_text_color=”#ffffff” button_use_icon=”off” locked=”on” button_text_size__hover_enabled=”off” button_text_size__hover=”null” button_one_text_size__hover_enabled=”off” button_one_text_size__hover=”null” button_two_text_size__hover_enabled=”off” button_two_text_size__hover=”null” button_text_color__hover_enabled=”off” button_text_color__hover=”null” button_one_text_color__hover_enabled=”off” button_one_text_color__hover=”null” button_two_text_color__hover_enabled=”off” button_two_text_color__hover=”null” button_border_width__hover_enabled=”off” button_border_width__hover=”null” button_one_border_width__hover_enabled=”off” button_one_border_width__hover=”null” button_two_border_width__hover_enabled=”off” button_two_border_width__hover=”null” button_border_color__hover_enabled=”off” button_border_color__hover=”null” button_one_border_color__hover_enabled=”off” button_one_border_color__hover=”null” button_two_border_color__hover_enabled=”off” button_two_border_color__hover=”null” button_border_radius__hover_enabled=”off” button_border_radius__hover=”null” button_one_border_radius__hover_enabled=”off” button_one_border_radius__hover=”null” button_two_border_radius__hover_enabled=”off” button_two_border_radius__hover=”null” button_letter_spacing__hover_enabled=”off” button_letter_spacing__hover=”null” button_one_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover=”null” button_two_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover=”null” button_bg_color__hover_enabled=”off” button_bg_color__hover=”null” button_one_bg_color__hover_enabled=”off” button_one_bg_color__hover=”null” button_two_bg_color__hover_enabled=”off” button_two_bg_color__hover=”null”]<\/p>\n [\/et_pb_comments][et_pb_text admin_label=”Related posts” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_3″][et_pb_sidebar area=”sidebar-1″ show_border=”off” _builder_version=”3.0.106″ locked=”on”]<\/p>\n [\/et_pb_sidebar][\/et_pb_column][\/et_pb_section][et_pb_section bb_built=”1″ admin_label=”Connect Title” module_class=”footer-section” _builder_version=”3.0.90″ background_color=”#1d1d1d” custom_padding=”0px||0px|” prev_background_color=”#ffffff” global_module=”380″][et_pb_row admin_label=”row” global_parent=”380″ parallax_method_1=”off” parallax_method_2=”off” parallax_method_3=”off” module_id=”footer-row” _builder_version=”3.0.89″ locked=”off”][et_pb_column type=”1_3″][et_pb_text admin_label=”Contact Us Title” global_parent=”380″ _builder_version=”3.0.74″ text_text_color=”#ffffff” background_size=”initial” background_position=”top_left” background_repeat=”repeat” background_layout=”dark”]<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Contact Us” global_parent=”380″ module_class=”contact-us” _builder_version=”3.17.6″ text_text_color=”#aaaaaa” background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off”]<\/p>\n Prof Mike Bromley (Centre Director)<\/strong> Dr Margherita Bertuzzi \u00a0<\/p>\n \u00a0<\/p>\n \u00a0<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″][et_pb_text admin_label=”Find Us Title” global_parent=”380″ _builder_version=”3.0.74″ text_text_color=”#ffffff” background_size=”initial” background_position=”top_left” background_repeat=”repeat” background_layout=”dark”]<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Address” global_parent=”380″ module_id=”address” _builder_version=”3.0.87″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” background_layout=”dark” use_border_color=”off” border_color=”#ffffff” border_style=”solid”]<\/p>\nRelated<\/h1>\n
Related posts:<\/h3>
Meet the team: Helen Harris<\/h2><\/div><\/div><\/a>
Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a>
Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>
Related<\/h1>\n
Related posts:<\/h3>
Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a>
Meet the team: Helen Harris<\/h2><\/div><\/div><\/a>
Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div>
Related<\/h1>\n
Related posts:<\/h3>
Meet the team: Helen Harris<\/h2><\/div><\/div><\/a>
Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a>
Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a><\/div>
Related<\/h1>\n
Related posts:<\/h3>
Meet the team: Helen Harris<\/h2><\/div><\/div><\/a>
Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a>
Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>
Related<\/h1>\n
Related posts:<\/h3>
Meet the PhD student: Dr Luthvia Annisa<\/h2><\/div><\/div><\/a>
Meet the team: Helen Harris<\/h2><\/div><\/div><\/a>
Meet the PhD student: Phurichaya (Jane) Khunthong<\/h2><\/div><\/div><\/a><\/div>
Contact Us<\/h4>\n
Email: mike.bromley@manchester.ac.uk<\/a><\/p>\n
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