Antimicrobial resistance network

Understanding antimicrobial resistance evolution to better combat drug-resistant infections.



Drug-resistant infections are a major threat to global health requiring new sustainable solutions. Resistance has evolved against all classes of antimicrobial.


Our goal is to harness improved understanding of the evolution of antimicrobial resistance (AMR) to design better treatment strategies that reduce the local, national, and global burden of drug-resistant infections.

The Antimicrobial Resistance Network is a community of more than 100 clinical and academic researchers who work across The University of Manchester and Manchester University NHS Foundation Trust and are focused on combating antimicrobial resistance.

The network brings together diverse expertise and technologies from across The University of Manchester with industrial partners and NHS clinicians to address this critical global challenge.

Our research will lead to:

  • development of more sustainable ways to use new and existing antimicrobials;
  • discovery of new antimicrobial targets in drug resistant pathogens;
  • development of new antimicrobials, anti-infectives, and vaccines;
  • development of new diagnostic tests for drug resistant infections.

Keep up-to-date with research, news and information on our blog.



Research challenges

The AMR Network seeks to improve the understanding of AMR evolution to develop and translate novel evolution-informed solutions that reduce the impact of drug-resistant infections on human health and wellbeing.

We have defined three interlinked research challenges that we need to tackle to achieve our aims.

Understanding the problem

We study the mutations, genes, and mobile genetic elements (like plasmids) that cause AMR, as well as the underlying molecular mechanisms and selective forces that drive variation in AMR evolution in natural and clinical environments.

We want to answer questions such as:

  • Why does AMR evolve?
  • What are the molecular causes of AMR?
  • How do prescribing practices and policies impact on AMR evolution?

Lead: Professor Michael Brockhurst

Key researchers:


Finding solutions

We are utilising our understanding of the evolution of AMR to:

  • devise better strategies for using existing drugs;
  • develop new diagnostic tests and sensors;
  • discover new antimicrobial agents and targets.

Lead: Dr Michael Bromley

Key researchers:


Translating solutions

We work with the NHS to bring new solutions into the clinic to help better diagnose and treat patients.

We also work to:

  • improve prescribing and stewardship of antimicrobials;
  • develop antimicrobial drugs and vaccines, with industrial partners
  • improve access to new technologies, with global partners.

Lead: Dr Tim Felton

Key researchers:

Our partnerships

The AMR Network is part of a wider group of infection and immunity researchers at Manchester.

We work closely with groups and organisations such as:

We also work collaboratively with research groups and companies around the world.

Our industrial partners include:

  • Pfizer
  • Roche Diagnostics
  • APIS
  • Du Pont
  • Blueberry Therapeutics
  • Evotec
  • F2G
  • Genon Laboratories
  • Syngenta
  • Pharmacelsus
  • PiQ Laboratories
  • Gilead
  • Synlab
  • Syngenics

For more information about partnerships and collaborating with us, please contact Professor Mike Bromley.


Training future scientists and clinicians

It is important for us to inspire, promote and support the next generation of researchers in antimicrobial resistance and infection biology.

We are committed to this at all levels of study, and our PIs, staff and postdoctoral researchers teach on numerous courses.

The Infection Academy

Our courses are delivered through our Infection Academy, which has access to over 100 world-leading experts in virology, bacteriology and mycology.

They have active research programmes covering evolutionary microbiology, immunology, microbiomes, drug and vaccine discovery, epidemiology, development of diagnostics, and antimicrobial stewardship.

This enables our courses to cover clinical and research programmes that explore a very broad range of themes with a high level of specialist support and supervision.

Related postgraduate taught courses

We provide training and support for MSc, MRes and MSci students from various master’s courses doing research projects. These include:

Doctoral training and postgraduate research

Our clinicians and academics are, at any one time, supporting over 150 PhD students from all over the globe in projects focused on antimicrobial resistance and microbial pathogenicity research.

Our integrated community of PhD students are supported from a variety of sources. These include MRC and BBSRC Doctoral Training Partnerships, charities, industry and international government schemes. We also offer a wide range of opportunities for self-funded studentships.

Learn more about our funded PhD programmes.

Explore opportunities for self-funded projects with our PhD project search.

Postdoctoral research and independent fellowships

We have a large and active community of postdoctoral researchers and independent research fellows working on a range of AMR research projects.

We are keen to hear from prospective independent research fellows who wish to join us at The University of Manchester by applying for fellowship funding from organisations such as:

  • Medical Research Council
  • Biotechnology and Biological Sciences Research Council
  • Natural Environment Research Council
  • Wellcome Trust.

For more information, please get in touch with the relevant research lead academic:


Find out about additional support offered by our Fellowship Academy.


Public engagement

We are passionate about engaging with the public and patients to improve understanding of the AMR crisis and how we can solve it together.

Recent projects include:

Join the network

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Contact us

Get in touch for more information about the Antimicrobial Resistance Network.

Professor Michael Brockhurst and Professor Michael Bromley (Academic Leads)
Dr Tim Felton (Clinical Lead)
Dr Bruce Humphrey (Research Development Manager)


Follow us on Twitter: @AMS_UoM