Rissanen E et al. Microglial activation, white matter tract damage, and disability in MS. Neurol Neuroimmunol Neuroinflamm. 2018 Mar 6;5(3):e443. doi: 10.1212/NXI.0000000000000443.OBJECTIVE: To investigate the relationship of in vivo microglial activation to clinical...
Category: Highlighted publications
Widespread microglial activation in multiple system atrophy.
Kübler D et al. Widespread microglial activation in multiple system atrophy. Mov Disord. 2019 Apr;34(4):564-568. doi: 10.1002/mds.27620. Epub 2019 Feb 6BACKGROUND: The pattern and role of microglial activation in multiple system atrophy is largely unclear. The...
Education modulates brain maintenance in presymptomatic frontotemporal dementia.
Gazzina S et al. Education modulates brain maintenance in presymptomatic frontotemporal dementiaJ Neurol Neurosurg Psychiatry. 2019 Oct;90(10):1124-1130. doi: 10.1136/jnnp-2019-320439. Epub 2019 Jun 10. OBJECTIVE: Cognitively engaging lifestyles have been associated...
Prospects and challenges of imaging neuroinflammation beyond TSPO in Alzheimer’s disease.
Boche D, Gerhard A, Rodriguez-Vieitez E; MINC Faculty. Prospects and challenges of imaging neuroinflamation beyond TSPO in Alzheimer's disease. Eur J Nucl Med Mol Imaging. 2019 Dec;46(13):2831-2847. doi: 10.1007/s00259-019-04462-w. Epub 2019 Aug 8. Neuroinflammation,...
Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study.
van der Ende EL et al. Serum neurofilament liught chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study. Lancet Neurol. 2019 Dec;18(12):1103-1111. doi: 10.1016/S1474-4422(19)30354-0. BACKGROUND: Neurofilament light chain (NfL) is a...
Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.
Moore KM et al. Lancet Neurol. 2019 Dec 3. pii: S1474-4422(19)30394-1. doi: 10.1016/S1474-4422(19)30394-1. [Epub ahead of print]BACKGROUND: Frontotemporal dementia is a heterogenous neurodegenerative disorder, with about a third of cases being genetic. Most of this...
Longitudinal investigation of neuroinflammation and metabolite profiles in the APPswe ×PS1Δe9 transgenic mouse model of Alzheimer’s disease.
Comparative Evaluation of Three TSPO PET Radiotracers in a LPS-Induced Model of Mild Neuroinflammation in Rats.
S. Sridharan, F.X. Lepelletier, W. Trigg, S. Banister, T. Reekie, M. Kassiou, A. Gerhard, R. Hinz, H. Boutin. Comparative Evaluation of Three TSPO PET Radiotracers in a LPS-Induced Model of Mild Neuroinflammation in Rats. Mol Imaging Biol. (2017);19(1):77-89. PURPOSE:...
Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia.
J.M. Pradillo, K.N. Murray, G.A. Coutts, A. Moraga, F. Oroz-Gonjar, H. Boutin, M.A. Moro, I. Lizasoain, N.J. Rothwell, S.M. Allan. Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia. Brain Behav Immun....
Multi-modal imaging of long-term recovery post-stroke by positron emission tomography and matrix-assisted laser desorption/ionisation mass spectrometry.
F. Henderson, P.J. Hart, J.M. Pradillo, M. Kassiou, L. Christie, K.J. Williams, H. Boutin, A. McMahon. Multi-modal imaging of long-term recovery post-stroke by positron emission tomography and matrix-assisted laser desorption/ionisation mass spectrometry. Rapid Commun...
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