Name: Omer Aziz

Job title: Consultant Surgeon

Location: The Christie NHS Foundation Trust

Email: omer.aziz2@nhs.net

Website: research.manchester.ac.uk/en/persons/omer.aziz

Specialities and research

Speciality

• Colorectal Surgery

Sub-speciality

• Peritoneal Tumour Surgery, Sarcoma Surgery

Research interests

Appendix cancer, colorectal cancer, peritoneal metastases, translational research, multi-omics, hyperthermic intraperitoneal chemotherapy, prehabilitation, role of microbiome in the metastatic process.

Type of research

IMPRESS2 is a clinical trial involving 18 UK gynae oncology centres aimed at reducing variation in treatment rates between centres.

Clinical trial experience

Chief investigator

Pseudomyxoma peritonei: building a European multicentric cohort to accelerate new therapeutic perspectives (PMPnet – Accelerator for PMP Research)

Principal investigator

Prehabilitation with wearables versus standard of care before major abdominal cancer surgery: a randomised controlled pilot study (Prehabilitation with wearables versus standard of care before major abdominal cancer surgery: a randomised controlled pilot study (trial registration: NCT04047524) | Surgical Endoscopy)

Co-Investigator

Priming the Tumour MicroEnvironment for Effective Treatment with Immunotherapy in Locally Advanced Rectal Cancer (PRIME-RT). Phase II Trial of Durvakumab (MEDI 4736) in combination with Extended Neoadjuvant Regimens in Rectal Cancer.

NEOadjuvant PembRolizumab In Stratified Medicine – ColoRectal Cancer (NEOPRISMCRC).

AZURE2 – a phase III, open-label, randomized study of perioperative dostarlimab monotherapy vs standard of care in previously untreated patients with T4N0 or stage III dMMR/MSI-H resectable colon cancer.

Pressurised IntraPeritoneal Aerosolised Chemotherapy (PIPAC) in the management of cancer of the colon, ovary and stomach: a randomised controlled phase II trial of efficacy in peritoneal metastases (PICCOS trial). This study aimed to assess the efficacy of a tri-modal prehabilitation programme delivered by smartwatches for improving functional fitness prior to major abdominal cancer surgery.

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