Publications

• Rebecca Preston, Anna Hoyle, Alana Stevenson Harris, Emily Williams, Tess Birtles, Joan Chang, Joe Swift, Alexander Eckersley, Rachel Lennon. Ageing impacts extracellular matrix turnover and remodelling in the kidney (Matrix Biology Plus, 2026)
• Ageing impacts extracellular matrix turnover and remodelling in the kidney (Kidney International Reports, 2026)
• Srinivasan S, Ramos-Lewis W, Morais MRPT, Chi Q, Soh AWJ, Williams E, Lennon R, Sherwood DR. A collagen IV fluorophore knock-in toolkit reveals trimer diversity in C. elegans basement membranes (Journal of Cell Biology, 2025)
• Williams E, Fresquet M, Bolas G, Kaseda S, Goncalves K, Steinsapir A, Adamson AD, Sherwood DR, Lennon R. Increased in vivo transduction of AAV-9 cargo in Alport podocytes (bioRxiv, 2025)
• Williamson SJ, Liebau M, Lennon R. Are we ACE-ing the early treatment of Alport syndrome? (Pediatric Nephrology, 2025)
• Williams E, Fresquet M, Li AS, Lawless C, Knight D, Colby E, Watson J, Welsh GI, Saleem MA, Lennon R. Proteomic profiling of kidney biopsies in nephrotic syndrome (Wellcome Open Research, 2024)
• De Gregorio V, Barua M, Lennon R. Collagen formation, function and role in kidney disease (Nature Reviews Nephrology, 2024)
• Preston R, Chrisp R, Dudek M, Morais MRPT, Tian P, Williams E, Naylor RW, Davenport B, Pathiranage DRJ, Benson E, Spiller DG, Bagnall J, Zeef L, Lawless C, Baker SM, Meng QJ, Lennon R. The glomerular circadian clock temporally regulates basement membrane dynamics and the podocyte glucocorticoid response (Kidney International, 2024)
• Stark Z, Byrne AB, Sampson MG, Lennon R, Mallett AJ. A guide to gene-disease relationships in nephrology (Nature Reviews Nephrology, 2024)
• Ng NSL, Yamamura T, Shenoy M, Stuart HM, Lennon R. Detection of Alport gene variants in children and young people with persistent haematuria (Pediatric Nephrology, 2024)
• Boeckhaus J, Gale DP, Simon J, Ding J, Zhang Y, Bergmann C, Turner AN, et al. SGLT2-Inhibition in patients with Alport syndrome (Kidney International Reports, 2024)
• Tian P, Koudis NM, Morais MRPT, Pickard A, Fresquet M, Adamson A, Derby B, Lennon R. Collagen IV assembly is influenced by fluid flow in kidney cell-derived matrices (Cells & Development, 2024)
• Sadeghi-Alavijeh O, Chan MM, Doctor GT, Voinescu CD, Stuckey A, Kousathanas A, Ho AT, Stanescu HC, Bockenhauer D, Sandford RN, Levine AP, Gale DP. Quantifying variant contributions in cystic kidney disease using national-scale whole-genome sequencing (Journal of Clinical Investigation, 2024)
• Gale DP, Gross O, Wang F, Esteban de la Rosa RJ, Hall M, Sayer JA, Appel G, et al. A Randomized Controlled Clinical Trial Testing Effects of Lademirsen on Kidney Function Decline in Adults with Alport Syndrome (Clinical Journal of the American Society of Nephrology, 2024)
• Wong K, Pitcher D, Braddon F, Downward L, Steenkamp R, Masoud S, et al. Description and Cross-Sectional Analyses of 25,880 Adults and Children in the UK National Registry of Rare Kidney Diseases Cohort (Kidney International Reports, 2024)
• Wong K, Pitcher D, Braddon F, Downward L, Steenkamp R, Annear N, et al. 02843-X”>Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort (Lancet, 2024)
• Chew C, Brand OJ, Yamamura T, Lawless C, Morais MRPT, Zeef L, et al. Kidney resident macrophages have distinct subsets and multifunctional roles (Matrix Biology, 2024)
• Roser Torra, Beata Lipska-Ziętkiewicz, Frederic Acke, Corinne Antignac, Jan Ulrich Becker, Emilie Cornec-Le Gall, et al. Diagnosis, management and treatment of the Alport syndrome: 2024 guideline on behalf of ERKNet, ERA and ESPN (Nephrology Dialysis Transplantation, 2024)
• Eckersley A, Yamamura T, Lennon R. Matrikines in kidney ageing and age-related disease (Current Opinion in Nephrology and Hypertension, 2023)
• Deltas C, Papagregoriou G, Louka SF, Malatras A, Flinter F, Gale DP, Gear S, Gross O, Hoefele J, Lennon R, Miner JH, Renieri A, Savige J, Turner AN. Genetic Modifiers of Mendelian Monogenic Collagen IV Nephropathies in Humans and Mice (Genes, 2023)
• Eckersley A, Morais MR, Ozols M, Lennon R. Peptide location fingerprinting identifies structural alterations within basement membrane components in ageing kidney (Matrix Biology, 2023)
• Perrone RD, Oberdhan D, Ouyang J, Bichet DG, Budde K, Chapman AB, Gitomer BY, Horie S, Ong ACM, Torres VE, Turner AN, Krasa H. OVERTURE: A Worldwide, Prospective, Observational Study of Disease Characteristics in Patients With ADPKD (Kidney International Reports, 2023)
• Naylor RW, Watson E, Williamson S, Preston R, Davenport JB, Thornton N, Lowe M, Williams M, Lennon R. Basement membrane defects in CD151-associated glomerular disease (Pediatric Nephrology, 2022)
• Preston R, Meng QJ, Lennon R. The dynamic kidney matrisome: is the circadian clock in control? (Matrix Biology, 2022)
• Savige J, Renieri A, Ars E, Daga S, Pinto AM, Rothe H, Gale DP, et al. Digenic Alport Syndrome (Clinical Journal of the American Society of Nephrology, 2022)
• Naylor RW, Lemarie E, Jackson-Crawford A, Davenport JB, Mironov A, Lowe M, Lennon R. A novel nanoluciferase transgenic reporter measures proteinuria in zebrafish (Kidney International, 2022)
• Gibson JT, Sadeghi-Alavijeh O, Gale DP, Rothe H, Genomics England Research Consortium, Savige J. Pathogenicity of missense variants affecting the collagen IV α5 carboxy non-collagenous domain in X-linked Alport syndrome (Scientific Reports, 2022)
• KDIGO Conference Participants. Genetics in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference (Kidney International, 2022)
• Jayadev R, Morais MRPT, Ellingford JM, Srinivasan S, Naylor RW, Lawless C, Li AS, et al. A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations (Science Advances, 2022)
• Daga S, Ding J, Deltas C, Savige J, Lipska-Ziętkiewicz BS, Hoefele J, Flinter F, Gale DP, et al. The 2019 and 2021 International Workshops on Alport Syndrome (European Journal of Human Genetics, 2022)
• Mohamed M, Tellez J, Bergmann C, Gale DP, Sayer JA, Olinger E. Pseudodominant Alport syndrome caused by pathogenic homozygous and compound heterozygous COL4A3 splicing variants (Annals of Human Genetics, 2022)