Publications

2019

  • Davies, A., Sefton, C., Wray, J.R., Shoop, R., Allen, T.-J., White, A., Harno, E., Adamson, A., Humphreys, N. and Coll, A.P. (2019) Metabolic Abnormalities of Chronic High-Dose Glucocorticoids Are Not Mediated by Hypothalamic AgRP in Male Mice. Endocrinology, 160, 964-978.

  • Binder, P., Wang, S., Radu, M., Zin, M., Collins, L., Khan, S., Li, Y., Sekeres, K., Humphreys, N., Swanton, E. et al. (2019). Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response. Circulation Research, 124, 696-711.

  • Minshawi, F., White, M.R.H., Muller, W., Humphreys, N., Jackson, D., Campbell, B.J., Adamson, A. and Papoutsopoulou, S. (2019) Human TNF-Luc reporter mouse: A new model to quantify inflammatory responses. Scientific Reports, 9, 193.

2018

  • Gurumurthy, C., Quadros, R., Adams, J., Alcaide, P., Ayabe, S., Ballard, J., Batra, S.K., Beauchamp, M.-C., Becker, K.A., Bernas, G. et al. (2018) Re-Evaluating One-step Generation of Mice Carrying Conditional Alleles by CRISPR-Cas9-Mediated Genome Editing Technology. bioRxiv, 393231.

  • Bagnall, J., Boddington, C., England, H., Brignall, R., Downton, P., Alsoufi, Z., Boyd, J., Rowe, W., Bennett, A., Walker, C.et al. (2018) Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation. Science Signaling, 11, eaaf3998.

  • Chang, J., Garva, R., Pickard, A., Chloé Yeung, C.-Y., Mallikarjun, V., Swift, J., Holmes, D.F., Calverley, B., Lu, Y., Adamson, A et al. (2019) Circadian control of the secretory pathway is a central mechanism in tissue homeostasis. bioRxiv, 304014.

  • Harper, C.V., Woodcock, D.J., Lam, C., Garcia-Albornoz, M., Adamson, A., Ashall, L., Rowe, W., Downton, P., Schmidt, L., West, S. et al. (2018) Temperature regulates NF-κB dynamics and function through timing of A20 transcription. Proceedings of the National Academy of Sciences, 115, E5243-E5249.

  • Mularczyk, E.J., Singh, M., Godwin, A.R.F., Galli, F., Humphreys, N., Adamson, A.D., Mironov, A., Cain, S.A., Sengle, G., Boot-Handford, R.P. et al. (2018) ADAMTS10-mediated tissue disruption in Weill–Marchesani syndrome. Human Molecular Genetics, 27, 3675-3687.

  • Pickard, A., Adamson, A., Lu, Y., Chang, J., Garva, R., Hodson, N. and Kadler, K.E. (2018) Collagen assembly and turnover imaged with a CRISPR-Cas9 engineered Dendra2 tag. bioRxiv, 331496.

  • Roostalu, U., Aldeiri, B., Albertini, A., Humphreys, N., Simonsen-Jackson, M., Wong Jason, K.F. and Cossu, G. (2018) Distinct Cellular Mechanisms Underlie Smooth Muscle Turnover in Vascular Development and Repair. Circulation Research, 122, 267-281.

2017

  • Daniels, M.J.D., Adamson, A.D., Humphreys, N. and Brough, D. (2017) CRISPR/Cas9 mediated mutation of mouse IL-1α nuclear localisation sequence abolishes expression. Scientific Reports, 7, 17077.

  • Richardson, R., Mitchell, K., Hammond, N.L., Mollo, M.R., Kouwenhoven, E.N., Wyatt, N.D., Donaldson, I.J., Zeef, L., Burgis, T., Blance, R. et al. (2017) p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate. PLOS Genetics, 13, e1006828.