Our services

We provide fast, affordable and reliable services for the most popular applications of genomic technologies.

The facility occupies purpose-built laboratory space in the AV Hill Building from where we support five main technology categories:

• Illumina sequencing
• real-time and digital PCR instruments
• Sanger sequencing
• digital nucleic acid analyses (NanoString Technologies)
• single cell analyses.

Post-doc level advanced support

We can discuss your project and provide advice on how you can utilise techniques that have been established within the facility.

We are particularly good at refining your analytical aims, and providing practical hands-on support or training on sample preparation and data analysis.

The main themes for advanced support are:

• proteomics (cells, media and tissues);
• advanced post-translational modifications analysis (custom designed analysis with manually verified data);
• MS Western Blotting (for the lowest possible detection limits for specified proteins);
• absolute quantification (validated and accurate determination of protein concentration).

We also provide advice and some support to those looking at new biological applications of mass spectrometry.

However, due to our remit of providing wide-ranging support to biological research, priority will be given to applications that are likely to benefit a significant number of other research groups.

Analysis only

For those with experience in sample preparation and data analysis we can offer a lower cost analysis only service, whereby facility staff will receive the samples, run them on the specified system with a specified method and the make the data available.

These customers have access to our informatics software available in our informatics suite.

In order to use this service we ask that customers comply with our sample submission guidelines, with samples having under gone the appropriate clean up procedure and transferred to the correct vials ready for analysis.

Informatics support

Understanding and interpreting mass spectrometry data can be challenging, even for those experienced in the technique, so the facility provides informatics support from our dedicated in-house informatician.

Advice and training can be provided on experimental design, processing your own data and determining significance from your results.

This support is particularly applicable to those using both the basic and advanced proteomics services.