Basics: Lipids and detergents and their effect on LC-MS

Basics: Lipids and detergents and their effect on LC-MS

Bio-MS community All Introductions Workflows Methods Basics UserStories Facility Glossary We have had increasing evidence that non-peptide molecules are coming through our sample prep techniques and affecting the LC-MS systems. We are pretty sure about the effect of...
Facility: Is accuracy important?

Facility: Is accuracy important?

Bio-MS community All Introductions Workflows Methods Basics UserStories Facility Glossary This post follows on from a conversation with Christoph Borchers of the University of Vancouver in which he states “Accuracy is not important, precision is everything”. This is a...
Basics: Protein solubilisation

Basics: Protein solubilisation

Bio-MS community All Introductions Workflows Methods Basics UserStories Facility Glossary To solubilise proteins you need to break proteins apart (see guide to protein-protein interactions for details on the forces that keep proteins together) and keep them apart. ...