COVID: why T cell vaccines could be the key to long-term immunity
Prof Sheena Cruickshank has written for The Conversation on the challenges posed by the Omicron variant of Covid-19 and how developing T-cell vaccines may be the key to unlocking long-term immunity from Covid:
Many of the vaccines designed to date – including Moderna’s, Pfizer’s and AstraZeneca’s – have focused on just one major target on the coronavirus: its spike protein. These vaccines have been tremendously effective at generating antibodies. They also stimulate a T cell response to the spike.
But now that we understand more about the role of T cells, the importance of having a broad T cell response, and the issue of antibodies waning, perhaps we should consider refocusing our vaccine strategies on generating T cells and on targeting more than just one protein.
You can read the full article here