Effectively implementing strategies to curb transmission of SARS-CoV-2 (the virus that causes COVID-19) requires understanding who is contagious and when. Whilst viral load (VL) on upper respiratory swabs has commonly been used to infer contagiousness, measuring viral...
Category: Journal papers
A SARS-CoV-2 outbreak in a plastics manufacturing plant
In March 2021, an outbreak of COVID-19 occurred at a plastics manufacturing workplace in the United Kingdom, and an initial investigation was conducted by Public Health England’s local Health Protection Team. After notification of this outbreak, the COVID-OUT team...
Excess mortality among essential workers in England and Wales during the COVID-19 pandemic: an updated analysis
During 2020, excess mortality during the COVID-19 pandemic varied over time and by occupation. Essential workers, particularly those in healthcare, had higher excess mortality than non-essential workers throughout 2020 in England and Wales.The first national lockdown...
Quantifying the risk of workplace COVID-19 clusters in terms of commuter, workplace, and population characteristics.
This study from Theme 1 researchers of the PROTECT NCS used novel national data linkages to identify potential risk factors of workplace COVID-19 clusters, including possible protective effects of vaccination and increased physical distance at work. This e-print...
A mathematical model for assessing transient airborne infection risks in a multi-zone hospital ward.
Airborne transmission is an infection route for many pathogens such as Tuberculosis (TB), Influenza and more recently SARS-CoV-2 (the virus that causes COVID-19). With respiratory diseases already being a major contributor to pressure on hospital systems such as the...
Differential Risk of SARS-CoV-2 Infection by Occupation: Evidence from the Virus Watch prospective cohort study in England and Wales
This paper by PROTECT theme 3 researchers and the Virus Watch community cohort study, investigates how occupational differences in SARS-CoV-2 infection risk has changed over time, and includes updated data from the Omicron wave in England and Wales. Most pronounced...
Surface sampling for SARS-CoV-2 in workplace outbreak settings in the UK, 2021-22
As part of the COVID-19 Outbreak investigation to Understand Transmission study (COVID-OUT) study, environmental surface sampling was conducted at workplaces reporting cases of COVID-19 within their workforce to establish areas of contamination within workplaces,...
SARS-CoV-2 detected on exhaled breath by facemask sampling predicts how likely someone is to transmit to their household better than upper respiratory tract swabs.
People who test positive for COVID-19 and breathe out virus are more likely to infect their household members than via virus sampled in their nose and throatPeople are most likely to breathe out high amounts of virus early on when they are infectedIf participants were...
Occupational differences in COVID-19 incidence, severity, and mortality in the United Kingdom: available data and framework for analyses
This methods paper, produced by researchers from Theme 3 of the PROTECT study, assesses the datasets available for investigating difference in COVID-19 mortality for workers in different occupations in the UK.All the datasets considered are found to have particular...
Room-Based Assessment of Mobile Air Cleaning Devices Using a Bioaerosol Challenge
The widespread transmission of the SARS-CoV-2 virus has increased scientific and societal interest in air cleaning technologies, and their potential to mitigate the airborne spread of microorganisms. In this paper, published in Applied Biosafety, researchers from...
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